Mifepristone-misoprostol medical abortion: home administration of misoprostol in guadeloupe

Guengant, Jean-Pierre; Bangou, J.; Elul, Batya; Ellertson, Charlotte

doi:10.1016/s0010-7824(99)00074-8

Cited by 32 publications

(23 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…However, successful self-administration of vaginal misoprostol at home and in hospital prior to medical termination of pregnancy has been reported in the literature. [38][39][40][41][42] It has previously been suggested that women of different cultural and ethnic backgrounds might have a completely different view regarding self-administration, 37 although our study does not support this view. It has been estimated that there are a large number of women at risk of not receiving a cervical priming agent pre-operatively in England and Wales.…”

Section: Discussioncontrasting

confidence: 93%

Fertility control: Oral versus self‐administered vaginal misoprostol at home before surgical termination of pregnancy: a randomised controlled trial

Oppegaard

Qvigstad

Nesheim

2005

BJOG

View full text Add to dashboard Cite

Objective To compare the impact of 400 mg oral versus selfadministered vaginal misoprostol at home on pre-operative cervical priming in both primigravid and multigravid women prior to first trimester surgical abortion.Design Randomised controlled trial.Setting Norwegian University Teaching Hospital.Sample Three hundred and thirty-eight women undergoing surgical abortion between 7 and 12 weeks of gestation.Methods The women were randomised to either 400 mg of oral misoprostol the evening before or 400-mg of self-administered vaginal misoprostol at home the same day as vacuum aspiration.Main outcome measures Pre-operative cervical dilatation, complications and acceptability.Results The median cervical dilatation was 6.2 mm (range 0-11 mm) for the women in the 400 mg oral misoprostol and 6.5 mm (range 0-11 mm) in the 400-mg vaginal misoprostol groups. The median pre-operative dilatation was larger in multigravidae (6.4 and 6.7 mm for the oral and vaginal routes, respectively) than in primigravidae (5.8 and 6.0 mm, respectively). In primigravidae, 19% achieved a pre-operative dilatation of ‡7 mm, with no significant difference between oral and vaginal dosage. In multigravidae, 52% achieved a pre-operative dilatation of ‡7 mm with vaginal dosage, compared with 36% with oral dosage (P = 0.03). There was no difference between non-immigrant versus immigrant women in pre-operative cervical dilatation. The 400-mg oral dosage group had a higher risk of bleeding, compared with the group receiving 400-mg vaginal misoprostol [odds ratio (OR) = 10.4; confidence interval (CI) 5.2-20.8]. There was no difference between non-immigrant and immigrant women in acceptability of self-administered vaginal misoprostol; almost all women found this administration route acceptable. Complications were minor and were distributed equally between the two dosage groups. ConclusionsThe vaginal route will result in a satisfactory dilatation in about half of multigravidae but is much less effective in primigravidae. The oral route does not lead to satisfactory dilatation in either group and is associated with a higher occurrence of pre-operative bleeding. Self-administered vaginal misoprostol at home is highly acceptable.

show abstract

Section: Discussioncontrasting

confidence: 93%

Fertility control: Oral versus self‐administered vaginal misoprostol at home before surgical termination of pregnancy: a randomised controlled trial

Oppegaard

Qvigstad

Nesheim

2005

BJOG

View full text Add to dashboard Cite

show abstract

“…Clinical trials from Canada, 7 Turkey 8,9 and the United States 10,11 report rates of complete abortion ranging from 91% to 98% for pregnancies up to 9 weeks when misoprostol is administered at home (Appendix A, available at: http://www.mariestopes.org/documents/Home-based%20 Medical-Abortion-Systematic-Review-Appendix.pdf ). Observational studies [12][13][14][15][16][17][18][19][20] have also shown that home-based medical abortion is well accepted and effective, with 86-98% of women reporting satisfaction with the method and complete abortion achieved in 87% to 98% of cases. However, none of these studies has compared home-based medical abortion with clinic-based protocols.…”

Section: Introductionmentioning

confidence: 99%

Comparative effectiveness, safety and acceptability of medical abortion at home and in a clinic: a systematic review

Ngô

Park

Shakur

et al. 2011

Bull. World Health Organ.

148

118

View full text Add to dashboard Cite

“…C'est ainsi que dans d'autres pays (États-Unis, Tunisie, Vietnam) l'obligation d'une hospitalisation a été supprimée et la patiente peut faire le choix de rester chez elle lors de la prise du misoprostol [5][6][7]. Déjà expérimentée en Guadeloupe [8], cette possibilité a été validée en France en 2001 dans le rapport de l'Anaes sur l'IVG avec certaines restrictions [9]. Par ailleurs la réforme de la loi sur l'IVG du 4 juillet 2001 a ouvert la possibilité de pratiquer des IVG sans hospitalisation dans le cadre d'un réseau de santé ville-hôpital [10].…”

Section: Introductionunclassified

Efficacité et acceptabilité de l'interruption volontaire de grossesse par méthode médicamenteuse pratiquée sans hospitalisation dans le cadre d'un réseau ville–hôpital : étude prospective sur 433 patientes

Faucher

Baunot

Madelenat

2005

Gynécologie Obstétrique & Fertilité

View full text Add to dashboard Cite

Mifepristone-misoprostol medical abortion: home administration of misoprostol in guadeloupe

Cited by 32 publications

References 11 publications

Fertility control: Oral versus self‐administered vaginal misoprostol at home before surgical termination of pregnancy: a randomised controlled trial

Fertility control: Oral versus self‐administered vaginal misoprostol at home before surgical termination of pregnancy: a randomised controlled trial

Comparative effectiveness, safety and acceptability of medical abortion at home and in a clinic: a systematic review

Efficacité et acceptabilité de l'interruption volontaire de grossesse par méthode médicamenteuse pratiquée sans hospitalisation dans le cadre d'un réseau ville–hôpital : étude prospective sur 433 patientes

Contact Info

Product

Resources

About