Migraine and neck pain: Mechanisms of comorbidity

Зенкевич, А. С.; Филатова, Е. Г.; Latysheva, N. V.

doi:10.14412/2074-2711-2016-1-29-34

Cited by 10 publications

(2 citation statements)

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“…Зенкевич и соавт. [25], в которой изучалась патогенетическая связь мигрени и коморбидных болевых синдромов. Авторы пришли к выводу, что с нарастанием частоты приступов мигрени увеличивается число коморбидных болевых синдромов (вероятность возникновения как минимум двух болевых синдромов при хронической мигрени более чем десятикратно превышает такую вероятность при эпизодической мигрени).…”

Section: сравнительный анализ болевого синдрома у пациенток с эндометunclassified

Features of pain syndrome in genital endometriosis and migraine

Bagirova

Chernukha

Филатова

2021

RJTAO

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Migraine is often concurrent with endometriosis; however, the mechanisms of comorbidity of these conditions are inadequately studied. Pain is considered as the most significant clinical symptom and maladaptive manifestation of both migraine and endometriosis. Studying the relationship between the clinical manifestations of pain syndrome in patients with endometriosis and migraine is important, since it will contribute to the understanding of the mechanisms of comorbidity of these diseases.Objective: to analyze the features of pain syndrome in patients with migraine and genital endometriosis to clarify the neurogenic mechanisms of their comorbid relationship.Patients and methods. A total of 125 patients who had gone to a gynecologist for endometriosis were examined for the presence of migraine. In accordance with the inclusion criteria, 79 patients (mean age, 34.68±7.11 years) with genital endometriosis confirmed by diagnostic laparoscopy participated in the further study. Two age-matched groups were formed: a study group consisted of 38 patients with endometriosis and concomitant migraine; a comparison group included 41 patients with endometriosis without migraine. All the patients underwent clinical neurological examination, questionnaire survey, pelvic ultrasound, assessment of the severity of pelvic pain according to the pelvic pain index, and determination of the level of central sensitization (CS) using the CS Inventory.Results and discussion. 42% out of the 125 patients who had visited their gynecologist for endometriosis suffered from concomitant migraine, which confirms the comorbidity of these diseases. Chronic pelvic pain (CPP), dysmenorrhea, dyspareunia, and dyschesia were more common in patients with endometriosis and migraine; there were more patients with asymptomatic endometriosis in the comparison group. The patients of the two groups did not differ in the presentation of different forms of endometriosis, which favors the leading role of central mechanisms in the pathogenesis of pain syndrome in comorbidity of these diseases.In addition, there was a statistically significant increase in the presentation of CPP and dysmenorrhea in patients with chronic migraine compared to those with episodic migraine and to those without migraine. Significantly higher levels of CS according to CSI and pelvic pain index were found in patients with chronic migraine and endometriosis, which suggests that CS plays a key role in the comorbidity of these diseases.Conclusion. The phenomenon of CS is one of the mechanisms of comorbidity of migraine and endometriosis, contributes to both the worsening of various painful manifestations of endometriosis and the increase in migraine attacks, thereby causing obvious maladaptation in patients. The role of CS in the comorbidity of migraine and endometriosis opens up possibilities for the elaboration of a comprehensive interdisciplinary approach to treating these diseases.

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Section: сравнительный анализ болевого синдрома у пациенток с эндометunclassified

Features of pain syndrome in genital endometriosis and migraine

Bagirova

Chernukha

Филатова

2021

RJTAO

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“…Based on the study of nictitating and nociceptive flexor reflexes (NR and NFR) in 63 patients with chronic and 40 patients with epizodic migraine, Zenkevich AS [9] concluded that in a large number of patients, neck pain is an indispensable component of the pathogenesis of chronic migraine [9].…”

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Dopplerographic Assessment of Blood Flow Parameters of Vertebral Arteries in Patients with Cervicogenic Headache Due to Arthrosis and Instability of Atlanto-Axial Junction

Ya¹

2018

TTSR

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Introduction: Cervicogenic Headache (CH) is a syndrome characterized by chronic hemicranial pain that is referred to the head from either bony structures or soft tissues of the neck. Factors such as: i. Stable uncomfortable positioning of the head;ii. Increased mobility of the upper cervical vertebrae with rotational movements;iii. A combination of external pressure over the occipital region and mobility of the cervical vertebrae on the symptomatic side causes or strengthens the existing headache. The leading role in the formation of the central nervous system is played by the irritation of the vegetative plexus of the vertebral arteries.Objective: Dopplerographic evaluation of blood flow parameters in vertebral arteries in patients with cervicogenic headache due to arthrosis and instability of the atlanto-axial junction. Materials and methods:A retrospective analysis of the results of Doppler ultrasound in the 2 nd and 3 rd segments of the Vertebral Artery (VA) was performed in 58 patients aged 21-38 years, who had X-ray and MRI diagnosed arthrosis and instability of the atlanto-axial junction; among the examined were 21 men and 37 women. The maximum Systolic Velocity (Vs), the end Diastolic Velocity (Vd), the Resistance Index (RI) in second and third segments of VA in the neutral spine and flexion position of the neck. The control group consisted of 27 people aged 19-36 years without chronic headache, absence of arthrosis of the atlanto-axial junction according to the results of X-ray or MRI. Dopplerography was conducted on a Philips HD 11XE device using a linear and microconvection transducers in the frequency range 5-10MHz and 4-9 MHz; MRI -General Electric, Signa HDI, 1.5T. Results:In the control group in the second segment of the VA, Vs was 50.3±5.1cm/s, RI -0.61±0.03; at the level of 3 rd segment-48.9±5.1cm/s, RI -0.58±0.03; at the rotation of the head -Vs 43.6±4.5cm/s, RI -0.62±0.03, respectively. In a patients with Atlanto-axial arthrosis in the second segment of the VA, Vs was 48.9±5.3cm/s, RI-0.56±0.03; at the level of 3 rd segment -45.3±4.9cm/s, RI-0.54±0.03; at the rotation of the head-37.2±4.1cm/c, RI-0.71±0.04 (P<0.05) respectively. In patients with atlanto-axial instability at the level of C5-C6, Vs amounted to 49.2±5.1cm/s, RI-0.59±0.03; at the level of 3-d segment of VA-Vs was 46.1±4.8cm/s, RI -0.58±0.03. When the head was turned to the side in patients with instability of the atlanto-axial junction, Vs was significantly lower compared to the control group (34.1±4.2cm/s and 43.6±4.5cm/s; RI more then in the second segment of the VA (P<0.05). Conclusion:Instability of atlanto-axial junction, especially in combination with arthrosis, is one of the common causes of cervicogenic headache in young people. The main pathogenetic mechanism of the onset of pain is changes in blood flow in the third segment of the vertebral arteries, especially during rotational movements.

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Migraine in children and adolescents: modern principles of diagnostics and treatment

Головачева

Golovacheva

Антоненко

2021

RJTAO

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Migraine is a nervous system disorder that affects 7.7% of children and can debut before the age of 3 years. As they get older, the incidence of migraine increases, and among adolescents, its prevalence reaches 15%. The disease can significantly reduce the child's daily activity, school performance. Migraine is the most common cause of headache in children and adolescents, but it is not always diagnosed; it is not uncommon for patients with migraine to be misdiagnosed and given ineffective treatment. An effective approach to the diagnosis of migraine in children is presented, diagnostic criteria for migraine according to the 3rd edition of International Classification of Headache Disorders are described. Special disorders in childhood are described – episodic syndromes in children associated with migraine. Migraine treatment in children includes four main approaches: 1) lifestyle recommendations; 2) migraine attack treatment; 3) nonpharmacological treatment; 4) migraine preventive pharmacotherapy. All of the listed approaches for the treatment of migraine in childhood are discussed in detail.

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Migraine and neck pain: Mechanisms of comorbidity

Cited by 10 publications

References 20 publications

Features of pain syndrome in genital endometriosis and migraine

Features of pain syndrome in genital endometriosis and migraine

Dopplerographic Assessment of Blood Flow Parameters of Vertebral Arteries in Patients with Cervicogenic Headache Due to Arthrosis and Instability of Atlanto-Axial Junction

Migraine in children and adolescents: modern principles of diagnostics and treatment

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