Migraine headache and depression in adults: a systematic Review and Meta-analysis

Amiri, Sohrab; Behnezhad, Sepideh; Azad, Esfandiar

doi:10.1007/s40211-018-0299-5

Cited by 40 publications

(31 citation statements)

References 54 publications

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“…Headache is a chronic pain condition also involving psychological aspects of the painful experience [78] where emotional stress is one of the main trigger factors [79]. There is evidence that suggests that headache sufferers exhibit higher anxiety and depression [80,81], and also sleep disturbances [82]. Furthermore, some primary headaches, e.g., migraine, are associated to specific personality traits, e.g., neuroticism [83].…”

Section: Scientific Evidence Of Cognitive Interventions For Headachesmentioning

confidence: 99%

Clinical Reasoning Behind Non-Pharmacological Interventions for the Management of Headaches: A Narrative Literature Review

Fernández‐de‐las‐Peñas

Plaza-Manzano

Arias-Buría

2020

IJERPH

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Headache is the clinical syndrome most commonly observed by neurologists in daily practice. Pharmacological and non-pharmacological treatments are commonly used for the management of headaches; however, the clinical reasoning behind these interventions is not properly applied. We conducted a narrative literature review using as data sources for academic PubMed, MEDLINE, EMBASE, AMED, CINAHL, EBSCO, PEDro, Cochrane Database of Systematic Reviews, Cochrane Collaboration Trials Register, and SCOPUS. This narrative literature review mainly considered systematic reviews, meta-analyses, randomised clinical trials, and expert opinions published after the year 2000 discussing clinical reasoning for application of non-pharmacological interventions in individuals with tension-type, migraine, and cervicogenic headaches. After the data extraction, we organized the literature thematically as follows: (1) mapping of theoretical aspects of non-pharmacological interventions; (2) summarizing most updated literature about effectiveness of non-pharmacological interventions grouped by targeted tissue and headache; (3) identifying research gaps in the existing literature and proposing hypotheses for better understanding of current clinical reasoning. We found that there are many non-pharmacological treatment strategies used for headaches, including beyond the tissue-based impairment treatments (bottom-up) and strategies targeting the central nervous system (top down). Bottom-up strategies include joint-biased, soft-tissue biased, or needling interventions, whereas top-down strategies include exercise and cognitive interventions. Evidence shows that the effectiveness of these interventions depends on the application of proper clinical reasoning, since not all strategies are effective for all headaches. For instance, evidence of non-pharmacological interventions is more controversial for migraines than for tension-type or cervicogenic headaches, since migraine pathogenesis involves activation of sub-cortical structures and the trigemino- vascular system, whereas pathogenesis of tension-type or cervicogenic headaches is most associated to musculoskeletal impairments of the cervical spine. We conclude that current literature suggests that not all non-pharmacological interventions are effective for all headaches, and that multimodal, not isolated, approaches seem to be more effective for patients with headaches. Most published studies have reported small clinical effects in the short term. This narrative literature review provides some hypotheses for discrepancies in the available literature and future research. Clinical reasoning should be applied to better understand the effects of non-pharmacological interventions.

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Section: Scientific Evidence Of Cognitive Interventions For Headachesmentioning

confidence: 99%

Clinical Reasoning Behind Non-Pharmacological Interventions for the Management of Headaches: A Narrative Literature Review

Fernández‐de‐las‐Peñas

Plaza-Manzano

Arias-Buría

2020

IJERPH

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“…They found that a pooled odds ratio (PR) of 1.95 and 95% confidence interval (CI) of 1.61-2.35 were obtained in studying the effects of migraine in depression. Friedman and coworkers [21] found a positive correlation between migraine and suicidal ideation. They reviewed over 14,000 patients and recorded odds of suicidal ideation to be 2.49-fold higher among individuals with migraine (OR: 2.49; 95% CI: 2.34-2.65) compared to those free of migraine.…”

Section: Introductionmentioning

confidence: 96%

“…In patients with migraines, depression is found to be a poor prognosis factor [19][20]. Amiri and coworkers published the famous metanalysis that links migraine and depression based on 16 selected articles [21]. They found that a pooled odds ratio (PR) of 1.95 and 95% confidence interval (CI) of 1.61-2.35 were obtained in studying the effects of migraine in depression.…”

Section: Introductionmentioning

confidence: 99%

Is There an Association Between Migraine and Major Depressive Disorder? A Narrative Review

Jahangir¹,

Adjepong²,

Al-Shami³

et al. 2020

Cureus

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Various studies on the association of migraine with depression are published. The comorbidity may upgrade health conditions up to a critical degree. Besides, the duration of symptoms and treatment may be prolonged. Moreover, these conditions can force substantial financial and social hardships on patients and their families. In this literature review, we intend to examine the evidence obtained on the possible associations between migraine and major depressive disorder (MDD). This review is focused on aminergic neurons. One of the variables associated with patients who experience both of these two diseases might have a history of assault. In migraine and MDD patients, genetic evidence, such as single nucleotide polymorphisms (SNP), was found to be one of the associations. Another theory concluded that actual headache diagnosed in patients who received no treatment manifests a history of anxiety, and later, the patients display severe somatic symptoms. In conclusion, there is a robust molecular genetic background, explaining the relationship between migraines and MDD. This correlated data renders a combination of both diagnoses as single separate entities. However, further studies are encouraged to point out the issue of treatment strategies.

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“…Migraine is common, and while the global prevalence is around one in seven people ( GBD 2016 Headache Collaborators, 2018 ), it is estimated that the lifetime consultation rate for headache in the United States is 79.8%, suggesting that, overall, migraine biology is more common than the rate of diagnosis suggests ( Lipton et al, 2018 ). Epidemiological studies have suggested that migraine is associated with other systemic conditions such as depression ( Bruti et al, 2012 ; Ligthart et al, 2013 ; Yang et al, 2016 ; Amoozegar, 2017 ; Peres et al, 2017 ; Amiri et al, 2019 ; Zhang et al, 2019 ), anxiety ( Wacogne et al, 2003 ; Seng et al, 2017 ), irritable bowel syndrome ( Cole et al, 2006 ; Cady et al, 2012 ; Chang and Lu, 2013 ; Lau et al, 2014 ; van Hemert et al, 2014 ; Cámara-Lemarroy et al, 2016 ; Le Gal et al, 2016 ; Perveen et al, 2016 ; Doulberis et al, 2017 ; Grassini and Nordin, 2017 ; Wu et al, 2017 ; Arzani et al, 2020 ), fibromyalgia ( Nicolodi and Sicuteri, 1996 ; Peres et al, 2001 ; Peres, 2003 ; Marcus et al, 2005 ; Ifergane et al, 2006 ; Vij et al, 2015 ; Cho et al, 2017 ; Do et al, 2018 ; Whealy et al, 2018 ; Penn et al, 2019 ), sleep disorders ( Cevoli et al, 2012 ; Engstrøm et al, 2013 ; Kim et al, 2017 ; Rains, 2018 ; Buse et al, 2019 ; Ferini-Strambi et al, 2019 ; Bertisch et al, 2020 ), and chronic fatigue ( Peres et al, 2002 ; Lucchesi et al, 2016 ; Seo and Park, 2018 ), as well as cognitive disorders ( Gil-Gouveia and Martins, 2017 , 2019 ; Vuralli et al, 2018 ; Lo Buono et al, 2019 ). Many reasons have been postulated for these associations, including comorbidities, cause and effect, and shared pathophysiological mechanisms.…”

Section: Introductionmentioning

confidence: 99%

Migraine Is More Than Just Headache: Is the Link to Chronic Fatigue and Mood Disorders Simply Due to Shared Biological Systems?

Karsan

Goadsby

2021

Front. Hum. Neurosci.

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Migraine is a symptomatically heterogeneous condition, of which headache is just one manifestation. Migraine is a disorder of altered sensory thresholding, with hypersensitivity among sufferers to sensory input. Advances in functional neuroimaging have highlighted that several brain areas are involved even prior to pain onset. Clinically, patients can experience symptoms hours to days prior to migraine pain, which can warn of impending headache. These symptoms can include mood and cognitive change, fatigue, and neck discomfort. Some epidemiological studies have suggested that migraine is associated in a bidirectional fashion with other disorders, such as mood disorders and chronic fatigue, as well as with other pain conditions such as fibromyalgia. This review will focus on the literature surrounding alterations in fatigue, mood, and cognition in particular, in association with migraine, and the suggested links to disorders such as chronic fatigue syndrome and depression. We hypothesize that migraine should be considered a neural disorder of brain function, in which alterations in aminergic networks integrating the limbic system with the sensory and homeostatic systems occur early and persist after headache resolution and perhaps interictally. The associations with some of these other disorders may allude to the inherent sensory sensitivity of the migraine brain and shared neurobiology and neurotransmitter systems rather than true co-morbidity.

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Migraine headache and depression in adults: a systematic Review and Meta-analysis

Cited by 40 publications

References 54 publications

Clinical Reasoning Behind Non-Pharmacological Interventions for the Management of Headaches: A Narrative Literature Review

Clinical Reasoning Behind Non-Pharmacological Interventions for the Management of Headaches: A Narrative Literature Review

Is There an Association Between Migraine and Major Depressive Disorder? A Narrative Review

Migraine Is More Than Just Headache: Is the Link to Chronic Fatigue and Mood Disorders Simply Due to Shared Biological Systems?

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