Migraine hémiplégique familiale et sporadique

Ducros, Anne

doi:10.1016/j.neurol.2007.10.003

Cited by 14 publications

(5 citation statements)

References 18 publications

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“…Further evidence of the importance of astrocyte function in the pathogenesis of CSD is derived from patients with familial hemiplegic migraine type 2, an autosomal-dominant migraine subtype [94], where the threshold for CSD is reduced by a mutation involving the astrocyte α2 subunit of Na + -K + -ATPase [95].…”

Section: Migrainementioning

confidence: 99%

Astrocyte–neuron interactions in neurological disorders

et al. 2009

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Astrocytes have long been considered as just providing trophic support for neurons in the central nervous system, but recently several studies have highlighted their importance in many functions such as neurotransmission, metabolite and electrolyte homeostasis, cell signaling, inflammation, and synapse modulation. Astrocytes are, in fact, part of a bidirectional crosstalk with neurons. Moreover, increasing evidence is stressing the emerging role of astrocyte dysfunction in the pathophysiology of neurological disorders, including neurodegenerative disease, stroke, epilepsy, migraine, and neuroinflammatory diseases.

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Section: Migrainementioning

confidence: 99%

Astrocyte–neuron interactions in neurological disorders

et al. 2009

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“…The growing knowledge of the genetic bases of familial hemiplegic migraine (FHM) [8] and the findings of epileptic seizures occurring independent of the migraine attacks in FHM families [9] have stimulated the interest on the comorbidity between migraine and epilepsy.…”

Section: Introductionmentioning

confidence: 99%

Comorbidity between headache and epilepsy in a pediatric headache center

et al. 2010

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The purpose of this study was to analyse the comorbidity between headache and epilepsy in a large series of children with headache (1,795). Fifty-six cases (3.1%) suffered from idiopathic headache and idiopathic or cryptogenic epilepsy or unprovoked seizures. There was a strong association between migraine and epilepsy: in migraineurs (46/56) the risk of epilepsy was 3.2 times higher when compared with tension-type headache, without significant difference between migraine with and without aura (P = 0.89); children with epilepsy had a 4.5-fold increased risk of developing migraine than tension-type headache. In cases with comorbidity, focal epilepsies prevailed (43/56, 76.8%). Migraineurs affected by focal epilepsies (36/56) had a three times higher risk of having a cryptogenic epilepsy (27/36, 75%) than an idiopathic epilepsy (9/36, 25%) (P = 0.003). In migraine with aura, epilepsy preceded migraine in 71% of cases. Photosensitivity (7/56, 12.5%) and positive family history for epilepsy (22/56, 39%) were frequent in cases with comorbidity.

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“…It can either run in families (familial hemiplegic migraine) or occur sporadically in an individual (sporadic hemiplegic migraine). 7,8 In our case, the clinical presentation met the diagnostic criteria for sporadic hemiplegic migraine, characterized by reversible motor weakness and visual-sensory auras, as defined by the international classification of headache disorders (ICHD-3). 9 To rule out other potential causes that could mimic migraine, neuroimaging was performed, revealing MMD as the underlying condition.…”

Section: Discussionmentioning

confidence: 69%

Moyamoya Disease Masquerading as Hemiplegic Migraine in a Child: A Case Report From India

Kumar,

Mathur

2024

JPA

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Moyamoya disease (MMD) is a chronic progressive steno-occlusive disease of the intracranial arterial vessels and their branches characterized by puff smoke appearance on angiography. Multifocal neurological insults and deficits are commonly observed in children with MMD. A 7-year-old boy presented with multiple episodes of transient hemiparesis preceded by headache, vomiting, and visual auras was initially labeled as sporadic hemiplegic migraine according to the International Headache Society criteria. However, the rare association of hemiplegic migraine with MMD compelled us to perform magnetic resonance imaging and digital subtraction angiography, which revealed MMD as the underlying cause for the alternating hemiplegia and headaches in the child.

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Migraine hémiplégique familiale et sporadique

Cited by 14 publications

References 18 publications

Astrocyte–neuron interactions in neurological disorders

Astrocyte–neuron interactions in neurological disorders

Comorbidity between headache and epilepsy in a pediatric headache center

Moyamoya Disease Masquerading as Hemiplegic Migraine in a Child: A Case Report From India

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