Migraine in bipolar disorder and schizophrenia: The hidden pain

ElGizy, Nancy; Khoweiled, Aref; Khalil, Mohamed A.; Magdy, Rehab; Khalifa, Dalia

doi:10.1177/00912174231178483

Cited by 4 publications

(2 citation statements)

References 31 publications

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“…Approximately 16% of the general population is affected by migraines, while recent evidence indicates that around 25% of individuals with bipolar disorder suffer from migraines ( 29 ). The most frequent type of pain in bipolar disorder patients with migraines is throbbing pain (63.7%) ( 38 ). Compared to those with only bipolar disorder, the coexistence of bipolar disorder and migraines is often associated with higher rates of depressive episodes and increased suicide risk ( 38 ).…”

Section: Discussionmentioning

confidence: 99%

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Global trends and hotspots in pain associated with bipolar disorder in the last 20 years: a bibliometric analysis

Zhao,

Zhou,

Jiang

et al. 2024

Front. Neurol.

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PurposeThe prevalence of comorbid pain and Bipolar Disorder in clinical practice continues to be high, with an increasing number of related publications. However, no study has used bibliometric methods to analyze the research progress and knowledge structure in this field. Our research is dedicated to systematically exploring the global trends and focal points in scientific research on pain comorbidity with bipolar disorder from 2003 to 2023, with the goal of contributing to the field.MethodsRelevant publications in this field were retrieved from the Web of Science core collection database (WOSSCC). And we used VOSviewer, CiteSpace, and the R package “Bibliometrix” for bibliometric analysis.ResultsA total of 485 publications (including 360 articles and 125 reviews) from 66 countries, 1019 institutions, were included in this study. Univ Toront and Kings Coll London are the leading research institutions in this field. J Affect Disorders contributed the largest number of articles, and is the most co-cited journal. Of the 2,537 scholars who participated in the study, Stubbs B, Vancampfort D, and Abdin E had the largest number of articles. Stubbs B is the most co-cited author. “chronic pain,” “neuropathic pain,” “psychological pain” are the keywords in the research.ConclusionThis is the first bibliometric analysis of pain-related bipolar disorder. There is growing interest in the area of pain and comorbid bipolar disorder. Focusing on different types of pain in bipolar disorder and emphasizing pain management in bipolar disorder are research hotspots and future trends. The study of pain related bipolar disorder still has significant potential for development, and we look forward to more high-quality research in the future.

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Section: Discussionmentioning

confidence: 99%

“…The most frequent type of pain in bipolar disorder patients with migraines is throbbing pain (63.7%) ( 38 ). Compared to those with only bipolar disorder, the coexistence of bipolar disorder and migraines is often associated with higher rates of depressive episodes and increased suicide risk ( 38 ).…”

Section: Discussionmentioning

confidence: 99%

Global trends and hotspots in pain associated with bipolar disorder in the last 20 years: a bibliometric analysis

Zhao,

Zhou,

Jiang

et al. 2024

Front. Neurol.

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Comorbidity of Sleep Disorders, Mental Illness, and Migraine or Headaches

Merrill,

Gibbons

2023

SN Compr. Clin. Med.

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This study assesses the comorbidity of mental illness, sleep disorders, and migraine/headaches among employees in a large organization in the USA. The comorbidity of migraine/headaches and sleep disorders or mental illness has been well studied. However, simultaneous comorbidity of all three is less well known. Analyses were based on the Deseret Mutual Benefit Administrator employee database, derived from billing codes for employees and their families during the years 2017–2021. Statistical analyses were performed and adjusted for age, sex, marital status, dependent children, annual household income, and year. The claims rate for migraine is 2.2% and for headache is 0.95%. The claims rate for sleep disorder is 12.2%, with 34.6% having comorbid mental illness, primarily in the form of depression (18.4%), anxiety (18.0%), and ADHD (4.0%). The claims rate for mental illness is 18.4%, with comorbid sleep disorders 22.9%: 17.5% with sleep apnea, 6.5% with insomnia, and 2.2% with hypersomnia. Those with a sleep disorder are 130% times more likely to have migraine and 91% more likely to have headaches. Corresponding values for mental illness are 160% and 116%. Those with a sleep disorder only, mental illness only, or both (versus neither) are 133%, 162%, and 289% more likely to experience migraine, respectively. Corresponding values for headache are 92%, 118%, and 187%. Sleep and mental disorders positively associate with migraine and headache, more so when both are involved. The positive associations are stronger for migraine than headache.

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