Migraine-tic syndrome: Two further case reports

Abstract

Background Migraine-tic syndrome was first reported in 2004 in a 44-year-old woman who had concomitant symptoms of both typical trigeminal neuralgia and migraine. We report here two further cases of migraine-tic syndrome and speculate on the relevance of this condition to the pathophysiology of headache. Case reports A 43-year-old woman presented with typical trigeminal neuralgia symptoms that preceded the onset of migraine headache; both headache types responded to treatment with sumatriptan. A 35-year-old woman presented with trigeminal neuralgia that consistently followed the onset of migraine headache. The former aspect responded to baclofen, but the migraine headache required treatment with amitriptyline. Discussion These two patients provide further support for the presence of an overlap syndrome of migraine-tic. We suggest that there is a common pathway for trigeminal neuralgia and migraine.

Two Cases of Hemicrania Continua–Trigeminal Neuralgia Syndrome: Expanding the Spectrum of Trigeminal Autonomic Cephalalgia‐Tic (TAC‐TIC) Syndrome

“…Therefore, with a simple coincidence rule, TN should more commonly occur with migraine or TTH. Very recently, Hinze et al 3 reported that there are just three cases of migraine-tic syndrome in the literature. Although a recent study indicates that migraine is a risk factor for the development of TN.…”

“…1 However, the coexistence of two rare primary headaches is scarce. 2 Trigeminal neuralgia (TN) has been reported with various other primary headaches such as migraine (migraine-tic syndrome), 3 cluster headache (clustertic syndrome), 4,5 and paroxysmal hemicrania (paroxysmal hemicrania-tic syndrome). [6][7][8] TN may also be associated with short-lasting unilateral neuralgiform headache with conjunctival injection and tearing (SUNCT) and short-lasting unilateral neuralgiform headache attacks with cranial autonomic symptoms (SUNA).…”