Migraine-triggered hemifacial spasm: three new cases

Barahona-Hernando, Raúl; Cuadrado, María‐Luz; García-Ptacek, Sara; Marcos-de-Vega, A; Jorquera, Manuela; Guerrero, Antonio; Ordás, C.M.; Muñiz, Susana Hernandez; Porta‐Etessam, Jesús

doi:10.1177/0333102412438976

Cited by 5 publications

(2 citation statements)

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“…In particular, each patient should be examined for preexisting eyelid or eyebrow ptosis, pseudoptosis of the eyelids, neck pain, and neck weakness. Patients with CM may have preexisting eyelid ptosis with frontalis compensatory activity (ie, a Babinski‐2 or Reverse Babinski sign associated with hemifacial spasm) . This involves an up‐going eyebrow due to compensation of the frontalis muscle for eyelid closure.…”

Section: Discussionmentioning

confidence: 99%

“…Patients with CM may have preexisting eyelid ptosis with frontalis compensatory activity (ie, a Babinski-2 or Reverse Babinski sign associated with hemifacial spasm). [19][20][21] This involves an up-going eyebrow due to compensation of the frontalis muscle for eyelid closure. The presence of any soft tissue under the orbital ridge and resting on the eyelid may contribute to pseudoptosis.…”

Section: Discussionmentioning

confidence: 99%

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Insights into the Functional Anatomy Behind the PREEMPT Injection Paradigm: Guidance on Achieving Optimal Outcomes

et al. 2017

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ObjectiveTo provide clinically relevant insights on the identification of the muscles and techniques involved in the safe and effective use of onabotulinumtoxinA for chronic migraine prophylaxis.BackgroundAlthough guidance on the use of onabotulinumtoxinA for chronic migraine is available, based on the Phase III Research Evaluating Migraine Prophylaxis Therapy (PREEMPT) clinical program, clinical experience has shown that insufficient understanding of the anatomy and function of the head and neck muscles may lead to undesirable outcomes and suboptimal efficacy.Design/MethodsEach muscle involved in the standardized PREEMPT injection paradigm is reviewed with a thorough description of each muscle's anatomy (ie, muscle description and location, innervation, vascular supply) and function. Key insights based on clinical experience are also provided to help improve outcomes.ResultsThe identification of the muscles in the PREEMPT injection paradigm should be based on each patient's unique anatomy and injections should be administered using the advised techniques. A thorough examination of the patient prior to treatment is also critical to determine if any preexisting conditions may increase the risk for unwanted outcomes and appropriate expectations should be communicated.ConclusionsThorough knowledge of the functional anatomy of the muscles involved in the standardized PREEMPT injection paradigm is critical to achieve the efficacy and safety observed in clinical trials. In addition, it is important to assess a patient's baseline condition to anticipate the risk for unwanted outcomes that may result from treatment.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%