Milbenallergie im HNO-Bereich: Bedeutung, Diagnostik und Therapieoptionen

Abstract

Allergic rhinitis (AR) affects ca. 20% of the population. Approximately one third of patients affected by AR are suffering from perennial rhinitis due to mite allergy. Perennial rhinitis is the form of the disease that is most frequently associated with other allergy-related comorbidities such as asthma and atopic dermatitis, sleep disorders, chronic sinusitis, eustachian tube dysfunction and others.The often non-specific symptoms and the insidious course may lead to misinterpretations in diagnosing the disease.Therapeutic options include allergen avoidance with regard to environmental measures, encasings and personal actions. Drug therapy in mite-AR consists mainly in the administration of mast cell stabilizers, H1-antihistamines, glucocorticosteroids (GCS), leukotriene receptor antagonists and decongestants. It is particularly important to ensure a good antiinflammatory activity. Thus, a combination of H1-antihistamine and topical nasal GCS seems to be a rational approach. The only causal treatment form besides allergen avoidance is allergen-specific immunotherapy 1.

Rhinitis allergica in storage mite allergy

“…Permanent nasal obstruction, sneezing, rhinorrhea, impaired ability to smell and taste, allergic skin eczema, and allergic conjunctivitis must be queried. But also asthmoid complaints such as dry cough or recurrent dyspnea, which indicate a progression to asthma, as well as sleep disturbances belong in the anamnesis discussion [40]. Similarly, patients may report a reduction in performance at work and school due to symptoms.…”

Evolution of subcutaneous allergen immunotherapy (part 1): from first developments to mechanism-driven therapy concepts

“…House dust mite allergy is a worldwide problem. Mites belonging to the Dermatophagoides genus are particularly relevant [51]. As a general rule, allergen extracts can be produced from purified mite bodies or culture extracts; the composition of extracts varies depending on the raw materials used [52][53][54].…”

Liebe Kolleginnen und Kollegen, liebe Freunde der LRO,

“…Neben verschiedenen hoch-interessanten Kasuistiken berichtet Herr Kurzweg über das Thema Sozialmedizinische Leistungsbewertung durch HNO-Ärzte im Rahmen der Begutachtung für die Deutsche Rentenversicherung [10]. In der Rubrik Facharztwissen HNO ist in diesem Heft auf einen wichtigen Artikel zur Allergietherapie und Allergie-Immuntherapie im Kindesalter von Ludger Klimek et al hinzuweisen [11], der mit 3 CME-Punkten bewertet wird [12]. Mit Fragen für die Facharztprüfung und einem traditionellen Beitrag zu Operationstechniken von Hautdefekten im Bereich der Wange, von Gerhard Rettinger, findet das Heft seinen runden Abschluss.…”