Mild and convenient one pot synthesis of Schiff bases in the presence of P2O5/Al2O3 as new catalyst under solvent-free conditions

One Pot Synthesis of Imines from Aromatic Nitro Compounds with a Novel Ni/SiO2 Magnetic Catalyst

“…Since the first preparation of imines was reported by Schiff more than a century ago [7], a variety of methods/ systems for the synthesis of imines have been described, such as ZnCl 2 [8], TiCl 4 [9], MgSO 4 -PPTS [10], alumina [11], Ti(OR) 4 [12], Er(OTf) 3 [13], MgSO 4 [14], MgClO 4 [15], P 2 O 5 /Al 2 O 3 [16], CuSO 4 [17], and NaHCO 3 [18], in which metal species act as Lewis acids to activate the carbonyl group as well as facilitating the removal of water. In the past few years, with the development of experimental techniques, some innovations were reported, including solid-state synthesis [19], solvent-free/clay/microwave irradiation [20], water suspension medium [21], solvent/ reflux [22], infrared irradiation/no solvent [23], K-10/ microwave [24], silica/ultrasound irradiation [25], NaH-SO 4 ÁSiO 2 /microwave/solvent-free [26], dirhodium Caprolactamate [27], [bmim]BF 4 /molecular sieves [28] and et al The methods/systems aforementioned showed some disadvantages such as the requirements of high reaction temperatures, prolonged reaction periods, moisture sensitive catalysts, large quantities of aromatic solvents, costly dehydrating reagents/catalysts and special instruments [25].…”

“…As an alternative, one pot system for imine synthesis has been under investigations, such as Rh 6 (CO) 16 [29], PdCl 2 (PPh 3 ) 2 /SnCl 2 /CO [30], Pd/C/H 2 [31], and Ru 3 (CO) 12 /CO [32]. However, these protocols required transition-metal catalysts, elevated pressures, high temperatures, which made them far from ideal for laboratory-scale synthetic chemistry.…”

Facile and Convenient Synthesis and Characterization of Novel Schiff Bases Involving Heterocyclic Ring through One Pot Multicomponent Reactions under Mild Conditions

“…In continuation of our current efforts on research, 11,[18][19][20] we are focused on the development of the multicomponent reaction and the utilization of these processes toward the synthesis of novel Schiff bases. In this study, we report a practical and efficient three component reactions by reacting heterocyclic aldehydes with other aldehydes and ammonium hydroxide at room temperature.…”

The One-Pot Three Components of Iodone, Schiff Base and Epoxide for Synthesis of Iodohydrins

“…In continuation of our work on enantioselective epoxidation [14][15][16][17][18][19] of nonfunctionalized olefins by chiral Co(II), Ni(II) and Cu(II) Schiff base complexes and in pursuit of better selectivity through electronic tuning in the catalyst, we are reporting here the applying catalyst in ring opening opexides.…”