Mild and Efficient Method for Decarboxylative Bromination of α,β‐Unsaturated Carboxylic Acids with Dess—Martin Periodinane.

Abstract

2006 Halogen compounds Q 0090 Mild and Efficient Method for Decarboxylative Bromination of α,β-Unsaturated Carboxylic Acids with Dess-Martin Periodinane. -A combination of Dess-Martin periodinane and tetraethylammonium bromide is highly efficient for the title procedure. -(TELVEKAR*, V. N.; AROTE, N. D.; HERLEKAR, O. P.; Synlett 2005, 16, 2495-2497; Dep. Pharm. Sci. Technol., Inst. Chem. Technol., Univ. Mumbai, Matunga 400 019, Mumbai, India; Eng.) -Mais 08-056

Oxidative Cleavage of Epoxides Using Aqueous Sodium Paraperiodate

“…Our group has been working extensively on the development of novel methodologies under mild reaction conditions using the various iodine reagents. [6,7] Sodium paraperiodate is commercially available as white crystalline solid. Because of its insolubility in almost all organic solvents and even in water, it has not been exploited until now.…”

Micellar Mediated Halodecarboxylation of α,β‐Unsaturated Aliphatic and Aromatic Carboxylic Acids—A Novel Green Hunsdiecker–Borodin Reaction

“…[4] In another report, Telvekar has taken up decarboxylative bromination of a, b-unsaturated carboxylic acids with DesMartin periodinane. [5] A perusal of literature shows micellar mediated organic reactions are of great interest because of the relationship in close parallelism with enzyme processes. [6] Rate and selectivity of catalytic reactions can be enhanced by micelles, which act as a kind of micro reactors.…”