Milestone Studies on Ion-exclusion Chromatography of Ionic and Nonionic Substances Utilizing Multifunctional Separation Mechanism of Ion-exchange Resins

Abstract

Ion-exclusion chromatography (IEC) is categorized as a type of ion chromatography and is recognized as a simple and convenien t water quality monitoring technology for a variety of ionic substances. This review, mainly focusing on historical milestone studies by authors, outlines the archives that concern to the separation sciences and practical applications obtained from a variety of IEC modes used for water-quality monitoring as following: (1) early-developed IEC; (2) IEC with enhanced conductivity detection of weak ionic substances; (3) IEC using nonionic substances eluents such as sugars or polyols; (4) vacancy IEC based on novel separation concept; (5) applications to the water quality monitoring of inorganic ionic-nutrients; (6) simultaneous IEC and cation-exchange chromatography of anions and cations; and (7) the multicomponent IEC combing different separation modes and detection methods with the expansion of to the applicable fields such as food analysis or material evaluations .

Solution- and gas-phase behavior of decavanadate: implications for mass spectrometric analysis of redox-active polyoxidometalates

“…33 Although in the past IEC has been applied almost exclusively to separation of weak organic acids (based on their sizes and p K a values 34 ), it can be used for separation of inorganic anions as well. 35,36 Since V10, as well as many smaller vanadates, are weak acids, we hypothesized that it may be possible to achieve their retention on IEC. Furthermore, partial reduction of V10 in solution should have an effect on the p K a values, and unless the redox equilibria are too fast on the chromatographic time scale ( e.g.…”

Multifunctional-separation-mode ion chromatography method for determining major metabolites during multiple parallel fermentation of rice wine

“…2A and B) owing to suppressed anion dissociation and accelerated penetration into the negatively charged layer on the resin. [24][25][26] Consequently, the retention times of acids such as cis-aconitate, a-ketoglutarate, phosphate, pyruvate, citrate, iso-citrate, malate, fumarate, and succinate increased with increasing phthalic acid concentration (pH 2.61-2.95) in the eluent, as shown in Fig. 2A.…”

Implementation of a conductivity cell electrode as an ion chromatography detector

“…14 The optimal separation conditions were obtained by mixing 15 mM tartaric acid and 2.5 mM 18-crown-6 eluent, according to a previous study. [15][16][17] Fig. 1 Schematic illustration of the proposed glass electrode sensor IC system.…”