Milieu-Initiated Inversion of the Aqueous Polyproline II/Beta Propensity in the Alanine Tripeptide: Energetics Origin of the Onset of Amyloid Formation

Abstract

Extending our earlier analogous study of the alanine dipeptide (ADP), we have now analyzed the effect of the external environment on the polyproline II (P) and β relative energies, the P/β propensity, of the alanine tripeptide (ATP) .