The present research is aimed to evaluate the diverse husbandry practices, ethno-veterinary practices, socio-economic status and distressing constraints of camel pastoralists inhabiting desert (Thal) areas of Pakistan, where they maintain herds of Marecha and Barela dromedaries in extensive production regimes. For this purpose, 200 pastoralists were selected at random to fill out an on-site questionnaire. According to the farmers’ responses, it was perceived that their living status had improved in the last decades due to the progressive optimization of camel productivity and herdsmen responsiveness. In contrast, calf mortality rates, some traditional husbandry practices and the lack of market investments continued to be the major constraints affecting camel overall production. Ethno-veterinary medicines are widely applied as primary health care, thus influencing the general health, production potentials and relief of camels in the study region. With this scenario, concerned stakeholders and authorized institutions must re-evaluate the urgent needs of indigenous communities; their education and husbandry skills to promote economic/ financial support in low-income remote areas. In turn, traditional communities will be adapted to the changing socio-economic and cultural values with regard to camel husbandry and welfare. Current societal perceptions and demands within this livestock production industry, where camels are conceived as a sustainable food security animal, if accomplished to the highest possible extent, will increase effectiveness of the camel value chain and breeders’ quality of life will be noticeably enhanced. However, this success could be multiplied if government may devise community education, veterinary cover, marketing facilitates and interest-free small loans for pastoralists.