Mind the gap: Incidence of osteoporosis treatment after an osteoporotic fracture – results of the Austrian branch of the International Costs and Utilities Related to Osteoporotic Fractures Study (ICUROS)

Malle, Oliver; Borgstroem, F.; Fahrleitner‐Pammer, Astrid; Svedbom, Axel; Dimai, S.V.; Dimai, Hans Peter

doi:10.1016/j.bone.2019.115071

Cited by 26 publications

(20 citation statements)

References 23 publications

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“…In several studies performed in various countries, the implementation of therapy for osteoporosis was assessed [13][14][15][16][17][18]. In general, only a small part of affected subjects are treated across different countries and continents.…”

Section: Discussionmentioning

confidence: 99%

“…In a study, covering 8 countries across Europe, about 75% of elderly women at high risk of osteoporosis-related fractures did not receive appropriate medication [13]. In an observation, performed in Austria only, 1 out of 10 men, and less than 2 out of 10 women received an adequate treatment for osteoporosis at the time of fracture [15]. In a large sample of 5704 patients in Canada, the major fracture history was not followed by osteoporosis medication [16].…”

Section: Discussionmentioning

confidence: 99%

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Changes in osteoporosis therapy in postmenopausal women from the RAC-OST-POL Study: a 10-year follow-up

Pluskiewicz¹,

Adamczyk²,

Drozdzowska³

2022

Polish Archives of Internal Medicine

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This report describes changes in the therapy for osteoporosis in female patients, a populationbased sample from the RAC-OST-POL Study, during a 10-year follow-up (between 2010 and 2020). The percentage of subjects without any therapy decreased over the observation period but the number of patients on antiresorptive therapy did not change and a general progress was thus observed due to increased calcium and/or vitamin D supplementation. Obviously, calcium and vitamin D supplement cannot replace antiresorptive medications with proven anti-fracture efficacy. Consequently, the level of care, provided to patients with postmenopausal osteoporosis did not improve during the 10-year observation period in the analyzed cohort.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Changes in osteoporosis therapy in postmenopausal women from the RAC-OST-POL Study: a 10-year follow-up

Pluskiewicz¹,

Adamczyk²,

Drozdzowska³

2022

Polish Archives of Internal Medicine

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“…According to results of the Austrian branch of the International Costs and Utilities Related to Osteoporotic Fractures Study (ICUROS), 68% of patients who presented with a fracture and who had a clear indication for osteoporosis treatment did not receive any such treatment. More importantly still, of patients who did not receive osteoporosis treatment at the time of fracture, 9 in 10 men and over 8 in 10 women were also not prescribed an adequate osteoporosis treatment thereafter [37]. In a study from France, only 16.7% received a specific osteoporosis treatment in the 12 months after a fracture.…”

Section: Discussionmentioning

confidence: 99%

Epidemiology and economic burden of fragility fractures in Austria

Muschitz¹,

Hummer²,

Grillari

et al. 2021

Osteoporos Int

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Fragility fractures are a frequent and costly event. In Austria, 92,835 fragility fractures occurred in patients aged ≥ 50 years in 2018, accruing direct costs of > 157 million €. Due to demographic aging, the number of fragility fractures and their associated costs are expected to increase even further. Introduction Fragility fractures are frequently associated with long hospital stays, loss of independence, and increased need for care in the elderly, with consequences often leading to premature death. The aim of this study was to estimate the number of fragility fractures and associated healthcare costs in Austria in 2018. Methods The number of in-patient cases with relevant ICD-10 diagnoses in all Austrian public hospitals was derived from discharge documentation of diagnoses and procedures covering all public hospitals in Austria. Fractures resulting from falls from standing height in patients aged ≥ 50 years were used as a proxy for fragility fractures, and the number of in-patient and out-patient cases was estimated. The direct costs of these cases were calculated using the average cost of the corresponding in-patient hospital stay and the average cost for the out-patient stay. ResultsThe present study estimated the number of fragility fractures (pelvis, thoracic and lumbar vertebra, hip, humerus, rib, forearm, and tibia) for 2018 at 92,835 or just over half of all fractures in patients aged ≥ 50 years, corresponding to a prevalence of 2,600 per 100,000 inhabitants of this age group. A constant increase in the proportion of fragility fractures among all fractures was observed with increasing age in both men and women. These fractures amounted to direct costs of > 157 million €. Conclusion Fragility fractures are a frequent and costly event in Austria. Due to the aging of the population, the number of fragility fractures and their associated costs is expected to increase even further.

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confidence: 99%

“…About one-third of the subjects were receiving supplementation with calcium and vitamin D at the time of fracture, and for those without prior supplementation less than half of the women and a quarter of the men were still taking supplements at 18 months. 8 Many factors influence the rate of initiation of drug treatment for secondary prevention of osteoporosis. An important factor is that of timing.…”

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confidence: 99%