Mindfulness-based intervention for clinical and subthreshold perinatal depression and anxiety: A systematic review and meta-analysis of randomized controlled trial

Leng, Ling; Yin, Xi Can; Ng, Siu Man

doi:10.1016/j.comppsych.2023.152375

Cited by 22 publications

(10 citation statements)

References 89 publications

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“…Early interventions that target maternal prenatal and postpartum depression and anxiety may be beneficial to promote positive parent–child interactions and also maternal perceptions of child’s temperament. 52 , 53 However, if other members of the family have this history, it may be more difficult to identify and intervene. Future research is needed to examine the relationship between toddler temperament, familial psychopathology and parental mental health problems.…”

Section: Discussionmentioning

confidence: 99%

Difficult Toddler Temperament – Prevalence and Associated Factors at 18-Month Follow-Up of a Birth Cohort

Bhadelia,

Barr,

John

et al. 2024

NDT

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Purpose Difficult temperament coupled with other risk factors may lead to mental health problems in childhood and have long-lasting effects in adolescence and adulthood. This study aimed to investigate the prevalence of parental perception of difficult temperament in toddlers and identify significant factors associated with individual and family-level sociodemographic risk factors. Patients and Methods The prevalence of parental perception of difficult temperament was derived from items in the 18-month follow-up questionnaire within the Watch Me Grow (WMG) longitudinal birth cohort study in a multicultural and socioeconomically disadvantaged community in Sydney, Australia. Data was available for 500 children and their parents. Descriptive analysis was used to calculate the participant characteristics and the prevalence of parental perception of difficult temperament, whereas multivariable logistic regression analysis was used to assess significant risk factors associated with a difficult temperament. Results Parental perception of difficult temperament in the cohort was 7.3% (n = 492). Findings of the multivariable logistic regression showed that screen time >2 hours a day (AOR 2.43, 95% CI: 1.2, 4.9), child not being read to (AOR 3.92, 95% CI: 1.8, 8.5), and family history of mental health problems (AOR 2.69, 95% CI: 1.1, 6.5) significantly increased the odds of having a difficult temperament. Conclusion Toddlers with difficult temperament were less likely to have received stimulatory experiences, and their families were more likely to be under greater stress. The findings emphasize the importance of parental support and anticipatory guidance in promoting nurturing care to facilitate child health and development, particularly in disadvantaged communities.

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Section: Discussionmentioning

confidence: 99%

Difficult Toddler Temperament – Prevalence and Associated Factors at 18-Month Follow-Up of a Birth Cohort

Bhadelia,

Barr,

John

et al. 2024

NDT

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“…The ndings suggest that interventions to ameliorate rumination may help reduce the severity of depression both directly and indirectly in pregnant women. Therefore, clinical interventionists need to recognize the importance of rumination and should consider developing positive rumination training programs to intervene in prenatal depression, such as mindfulness-based interventions [74], which are designed to help pregnant women actively accept negative thoughts caused by perceived stress without judgment, and shift the focus from perceived stress to breathing to improve depression.…”

Section: Discussionmentioning

confidence: 99%

The mediating and moderating role of rumination and cognitive reappraisal between perceived stress and prenatal depression: a multicenter cross-sectional study in southeast China

Wang,

Fang,

Yang

et al. 2023

Preprint

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Background Prenatal depression is one of the most prevalent psychiatric disorders among maternal. Perceived stress plays an important role in the onset of prenatal depression, however, the underlying mechanisms between them are not well understood. We aimed to explore the mechanisms from rumination(risk factors) and cognitive reappraisal(protective factors) perspectives, which may be used to design interventions to improve prenatal depression. Methods A multicenter cross-sectional survey of 1055 maternal were enrolled using a convenience sampling method from June 2020 to January 2021 and was conducted in five hospitals in Guangzhou, southeastern China. A moderated mediation model was performed to examine the role of rumination(Ruminative Responses Scale, RRS), and cognitive reappraisal(Emotional Regulation Questionnaire, ERQ) in the relationship between perceived stress(Perceived Stress Scale 10, PSS-10) and prenatal depression(Edinburgh Postpartum Depression Scale, EPDS). Results The prevalence of prenatal depression was 37.53%. There was a significant correlation among perceived stress, rumination, cognitive reappraisal, and prenatal depression(all P < 0.001). Rumination played a partial mediating role in the relationship between perceived stress and prenatal depression, accounting for 58.92% of the total effect. Moreover, the indirect effect of rumination in this link was moderated by cognitive reappraisal. This mediation effect was stronger for pregnant women with lower levels of cognitive reappraisal(P < 0.001). Conclusions The study provides powerful evidences through a large maternal sample for the mediating role of rumination and the moderating role of cognitive reappraisal between perceived stress and prenatal depression. Ongoing clinical care and targeted interventions may need to carry out from the perspective of rumination according to the different cognitive levels of maternal.

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“…Consistent evidence has been identified for mindfulness [ 20 – 23 ] and to some degree for self-compassion [ 20 , 22 , 23 ] as possible mediators of the effect of training the mind. Systematic reviews and meta-analyses on the effectiveness of MBIs on depression, anxiety and stress during pregnancy in both clinical and non-clinical populations have also increased rapidly in recent years [ 24 – 28 ]. One systematic review and meta-analysis examined the effect of MBIs on clinical and subthreshold perinatal depression and anxiety [ 24 ].…”

Section: Introductionmentioning

confidence: 99%

“…Systematic reviews and meta-analyses on the effectiveness of MBIs on depression, anxiety and stress during pregnancy in both clinical and non-clinical populations have also increased rapidly in recent years [ 24 – 28 ]. One systematic review and meta-analysis examined the effect of MBIs on clinical and subthreshold perinatal depression and anxiety [ 24 ]. A strength of the meta-analysis was a thorough assessment of symptom levels at baseline.…”

Section: Introductionmentioning

confidence: 99%

“…The effect on anxiety was also significant, but considered preliminary due to the current unavailability of high quality research. Importantly, no significant difference on effect was found when MBIs were delivered in person or through digital means [ 24 ], which could help remove barriers to treatment. Another systematic review and meta-analysis focusing on perinatal depression alone showed that MBIs delivered during pregnancy significantly mitigated the severity of depressive symptoms up to three months after childbirth, but that the effect tended to diminish after six months [ 25 ].…”

Section: Introductionmentioning

confidence: 99%

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The effect of an adapted Mindfulness-Based Stress Reduction program on mental health, maternal bonding and birth outcomes in psychosocially vulnerable pregnant women: a study protocol for a randomized controlled trial in a Danish hospital-based outpatient setting

Skovbjerg,

Sumbundu,

Kolls

et al. 2023

BMC Complement Med Ther

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Background Stress and mental disorders in pregnancy can adversely affect the developing fetus. Women with a preconception history of mental disorders or of psychosocial vulnerabilities are at increased risk of experiencing perinatal stress or mental health problems. Mindfulness-Based-Stress-Reduction (MBSR) is an acceptable intervention for pregnant women and has a growing evidence-base with meta-analyses consistently pointing to reductions in symptoms of stress, anxiety and depression. This study protocol aim to address the need for a wider array of evidence-based and non-pharmacological options during pregnancy to reduce stress and improve mental health in a psychosocially highly vulnerable group of women. Methods Pregnant women with a preconception history of mental disorders or psychosocial vulnerabilities (n = 240) will be recruited from an obstetric ambulatory clinic at Copenhagen University Hospital, Hvidovre, Denmark. Recruitment for the study began in March 2022 and will continue until the desired number of participants is reached. Consenting pregnant women will be randomized to one of two study arms, an adapted MBSR program as add on to usual care or usual care alone. The primary outcome is mental wellbeing at nine months post-randomization. Secondary and exploratory outcomes include stress, anxiety, depression, and maternal antenatal attachment, experience of childbirth, delivery and mode of delivery. Mindfulness and self-compassion are examined as possible mediators of the effect on outcomes. Discussion Teaching the skills of mindfulness meditation to a psychosocially vulnerable group of pregnant women could prove a viable and non-pharmacological approach to improve mental health and wellbeing during pregnancy, reduce stress and support the transition to parenthood. Mindfulness-Based Stress Reduction does not target a particular group, and results from the study is thus of potential relevance for pregnant women in general as a means of reducing stress and improving perinatal mental health and wellbeing. Trial registration ClinicalTrials.gov: NCT05300646. Registered March 29, 2022.

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Mindfulness-based intervention for clinical and subthreshold perinatal depression and anxiety: A systematic review and meta-analysis of randomized controlled trial

Cited by 22 publications

References 89 publications

Difficult Toddler Temperament – Prevalence and Associated Factors at 18-Month Follow-Up of a Birth Cohort

Difficult Toddler Temperament – Prevalence and Associated Factors at 18-Month Follow-Up of a Birth Cohort

The mediating and moderating role of rumination and cognitive reappraisal between perceived stress and prenatal depression: a multicenter cross-sectional study in southeast China

The effect of an adapted Mindfulness-Based Stress Reduction program on mental health, maternal bonding and birth outcomes in psychosocially vulnerable pregnant women: a study protocol for a randomized controlled trial in a Danish hospital-based outpatient setting

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