Mindfulness-based interventions for substance use disorders

Goldberg, Simon B.; Pace, Brian T.; Griskaitis, Matas; Willutzki, Reinhard; Skoetz, Nicole; Thoenes, Sven; Zgierska, Aleksandra; Rösner, Susanne

doi:10.1002/14651858.cd011723.pub2

Cited by 22 publications

(9 citation statements)

References 170 publications

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“…This low attendance rate might be driven by the inclusion of patients who used amphetamine or methamphetamine, both of which were negatively associated with attendance. While this suboptimal adherence rate is similar to rates observed in other group therapies for SUD ( 13 , 18 ), an increased adherence might lead to even stronger intervention effects.…”

Section: Discussionsupporting

confidence: 69%

Evaluation of the multimodal DELTA therapy for adolescents with substance use disorders: an exploratory pilot trial

Basedow,

Kuitunen-Paul,

Wiedmann

et al. 2024

Front. Psychiatry

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BackgroundIn order to address the lack of manualized treatment programs for adolescents with substance use disorders (SUDs), we developed a manualized group intervention (DELTA). DELTA focusses on substance use reduction and abstinence as well as alleviation of SUD symptoms via additional modules for co-occurring disorders. The goal of this exploratory trial was to assess if DELTA can be conducted in adolescent SUD patients and if participation is related to reductions in substance use, SUD-related problems, and further psychopathologies.MethodWe recruited adolescents at a psychiatric outpatient unit, which were then allocated to either DELTA intervention group (N = 85) or to a waiting-list control group (WL, N = 61) based on parental decision to start a therapy or not. Self-report measures were used as primary outcomes (substance use via interview, use-related problems via DUDIT—Drug Use Disorder Identification Test) and secondary outcomes (psychopathologies via YSR—Youth Self Report). T-tests and Pearson correlations were used to analyze between-group differences across time.ResultsOn average, participants attended M = 7.7 (SD = 5.1) of the 16 sessions. Substance use and use-related problems regarding all substances but nicotine was decreased after the intervention, with small to medium not significant effects in favor of DELTA. Self-reported psychopathologies were also reduced at follow-up, with non-significant advantages for DELTA.ConclusionDELTA showed small effects on SUD-related and depression-related variables. However, the interpretation is limited by the small sample size. Nonetheless, the DELTA intervention is viable in SUD outpatient treatment and will be further evaluated.Clinical trial registration: The study was registered at clinicaltrials.gov under NCT03444974. Registered February, 26th 2018 (https://clinicaltrials.gov/ct2/show/NCT03444974).

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Section: Discussionsupporting

confidence: 69%

Evaluation of the multimodal DELTA therapy for adolescents with substance use disorders: an exploratory pilot trial

Basedow,

Kuitunen-Paul,

Wiedmann

et al. 2024

Front. Psychiatry

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“…Even though the main result is comparable to other studies, our inconsistency exploration supports the need for the future developments in mindfulness research recommendations. In fact, a 2021 Cochrane review on MBIs in addiction came to similar conclusions, although craving data was not pooled [6]. Thus, our analysis contributes to the different independent evaluations of MBIs in addiction, revealing inconsistency issues, raising the question of the overly heterogeneous methodological approaches to studying mindfulness interventions.…”

Section: Discussionmentioning

confidence: 65%

“…Mindfulness can be defined as a state of consciousness in which a person is fully focused on their experience of the present moment with non-judgmental curiosity and an open attitude [5,6]. Trait mindfulness or dispositional mindfulness describes a predisposition to be mindful in everyday life, and state mindfulness is attained during mindfulness meditation practice [7,8].…”

Section: Introductionmentioning

confidence: 99%

Mindfulness interventions for craving reduction in substance use disorders and behavioral addictions: systematic review and meta-analysis of randomized controlled trials

Demina,

Petit,

Meille

et al. 2023

BMC Neurosci

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Background High-quality evidence is still required to affirm the efficacy of mindfulness-based interventions (MBIs) in craving reduction. MBIs may be particularly appropriate for this purpose given the neurobiological mechanisms of addiction with automatic behavior in response to the negative affect. In this systematic review and meta-analysis, we aimed to study the efficacy of MBIs in craving reduction and to synthetize the newly published data. Methods We searched four databases and three clinical trial registries for randomized controlled trials (RCTs) up to August 2023, including studies with MBIs in all types of substance use disorders or behavioral addictions. We chose as our outcome of interest the change from the baseline of craving measures at posttreatment. Standardized mean difference was used as an effect size estimator. Results We included 17 RCTs with 1228 participants. The overall effect size was estimated at -0.70 (95% CI -1.15, -0.26) in favor of MBIs. Conclusion Due to the high inconsistency (I2 = 92%), we were unable to conclude that there is a medium to large effect size. Overall risk of bias was high for most studies, and the GRADE approach detected a low quality of evidence. Previous clinical and fundamental research suggest that MBIs have a promising potential in addiction medicine. However, further investigation of whether MBIs effectively reduce craving is needed, and innovative solutions for resolving methodological limitations in MBI research are warranted. Trial registration PROSPERO registration ID CRD42020221141.

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“…21 Although MBIs may improve quality of life and mood, a 2021 meta-analysis revealed uncertain benefit of MBIs in SUD-related treatment outcomes specifically. 22…”

Section: Stress Management and Development Of Coping Strategiesmentioning

confidence: 99%