Mineral deficiency status of ranging zebu (Bos indicus) cattle around the Gilgel Gibe catchment, Ethiopia

Dermauw, Véronique; Kechero, Yisehak; Duguma, Belay; Hecke, Thomas Van; Laing, Gijs Du; Duchateau, Luc; Janssens, Geert

doi:10.1007/s11250-012-0337-4

Cited by 19 publications

(18 citation statements)

References 17 publications

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“…The evolution of plasma Fe concentration over time did not differ between the 2 breed types of cattle. However, zebu cattle did have more variable and greater liver Fe concentrations than crossbred cattle, which were also greater than found in previous research in the area (Dermauw et al, 2013a). Although this difference seems to contradict the ceruloplasmin explanation of Hansen et al (2010), dietary Cu levels were lower than in the supplemented study group of Hansen et al (2010), and therefore, the range in Cu status is much smaller in our study.…”

Section: Discussioncontrasting

confidence: 84%

“…Mineral imbalances in the soil and consequently in the plants growing on this soil often aggravate this situation (Haque et al, 1993). In Ethiopia, copper deficiency is a frequent problem when grazing on pastures, as low levels of Cu are accompanied by high levels of Mo and S and very high levels of Fe (Roeder, 1980;Faye and Grillet, 1984;Faye et al, 1991;Dermauw et al, 2013a). Consequently, deficiencies of Cu are to be expected in cattle in these regions.…”

Section: Introductionmentioning

confidence: 99%

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A disparate trace element metabolism in zebu (Bos indicus) and crossbred (Bos indicus × Bos taurus) cattle in response to a copper-deficient diet1

Dermauw

Cuyper

Duchateau

et al. 2014

Journal of Animal Science

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Copper deficiency is a commonly diagnosed problem in cattle around the globe. In Jimma, Ethiopia, 8 zebu (Bos indicus) and 8 zebu × Holstein Friesian cross (Bos taurus × Bos indicus) heifers were used in an 11-wk study to investigate breed type differences and effects of Cu deficiency on concentrations of trace elements in plasma and edible tissues as well as mRNA expression of Cu-related genes. Heifers were fed a grass diet (6.4 ± 0.2 [SEM] mg Cu/kg DM) supplemented with 1 mg Mo/kg DM in wk 1 to 4 and 2 mg Mo/ kg DM in wk 5 to 11, with blood samples collected every 2 wk and tissue collection postmortem. Plasma, liver, kidney, and semitendinosus and cardiac muscle were analyzed for Zn, Cu, Fe, Se, Mo, Co, and Mn. Expression of mRNA Cu-related genes was measured in aorta (lysyl oxidase [LOX] ) as well as the Se-related glutathione peroxidase 1 (Gpx1). Zebu cattle maintained initial plasma Cu concentrations just below the threshold value for deficiency, whereas crossbred cattle gradually became severely Cu deficient over time (P < 0.001). In contrast, plasma Zn and Co were greater in zebu cattle at the onset of the trial but became similar to crossbred cattle towards the end of the trial (P < 0.001). Liver Cu (P = 0.002) and Fe (P 0.001), kidney Se (P < 0.001), and kidney and cardiac muscle Co (P 0.001) concentrations were greater in zebu than in crossbred cattle. Increased hepatic mRNA expression of the Cu regulatory genes Atp7b, Ctr1 (P = 0.02), CCS (P = 0.03), and Cox17 (P = 0.009) and Cu-related Sod1 (P = 0.001) as well as the Se-related Gpx1 (P 0.001) were greater in zebu than in crossbred cattle. However, duodenal mRNA expression of DAO (P = 0.8) and Mt1a (P = 0.2) and aortic expression of LOX (P = 0.8) were not different. Both the differences in Cu status indices (plasma and liver concentrations) and hepatic mRNA expression of Cu regulatory genes point to the possibility of a more efficient use of dietary Cu in B. indicus as compared to B. taurus × B. indicus cattle resulting in greater sensitivity to Cu deficiency in B. taurus crossbred cattle. initial plasma Cu concentrations just below the threshold value for deficiency, whereas crossbred cattle gradually became severely Cu deficient over time (P < 0.001). In contrast, plasma Zn and Co were greater in zebu cattle at the onset of the trial but became similar to crossbred cattle towards the end of the trial (P < 0.001). Liver Cu (P = 0.002) and Fe (P ≤ 0.001), kidney Se (P < 0.001), and kidney and cardiac muscle Co (P ≤ 0.001) concentrations were greater in zebu than in crossbred cattle. Increased hepatic mRNA expression of the Cu regulatory genes Atp7b, Ctr1 (P = 0.02), CCS (P = 0.03), and Cox17 (P = 0.009) and Cu-related Sod1 (P = 0.001) as well as the Se-related Gpx1 (P ≤ 0.001) were greater in zebu than in crossbred cattle. However, duodenal mRNA expression of DAO (P = 0.8) and Mt1a (P = 0.2) and aortic expression of LOX (P = 0.8) were not different. Both the differences in Cu status indices (plasma and liver concentrations) and hepatic mRNA ...

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Section: Discussioncontrasting

confidence: 84%

Section: Introductionmentioning

confidence: 99%

A disparate trace element metabolism in zebu (Bos indicus) and crossbred (Bos indicus × Bos taurus) cattle in response to a copper-deficient diet1

Dermauw

Cuyper

Duchateau

et al. 2014

Journal of Animal Science

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“…Concomitantly with the low dietary trace element supply found in the Gilgel Gibe catchment, low trace element concentrations were found in transport and storage pools of sampled zebu-influenced cattle in the region (Dermauw et al, 2013a(Dermauw et al, , 2014a. More specifically, Cu deficiency was observed in almost half of the sampled animals, based on status evaluation by means of plasma and liver samples (Figure 2).…”

Section: Results and Conclusionmentioning

confidence: 88%

“…In two studies, individual plasma and pooled herd faeces were sampled in adult zebu cattle grazing at the catchment (n = 90) and liver in adult zebu bulls slaughtered at the local abattoir (n = 53) (Dermauw et al, 2013a) and trace element concentrations in these samples were determined. Meanwhile, the impact of sex, age, body condition and the presence of parasitic infections was analysed.…”

Section: Figure 1 Zebu Oxes Ploughing the Land At The Gilgel Gibe Camentioning

confidence: 99%

Trace element nutrition in the tropical zebu cattle type. Lessons from the Gilgel Gibe catchment, Ethiopia

Dermauw

2014

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In the tropics, cattle are majorly dependent on natural pastures growing on poor soils and as a result prone to trace element deficiencies. This work investigated several aspects of trace element nutrition in zebu (Bos indicus) cattle, the most widely used cattle type in the tropics. Through several trials conducted at the Gilgel Gibe catchment, Ethiopia, we aimed to study factors influencing the flow of trace elements from soil to plant and grazing zebu cattle, and to investigate the impact of trace element status on health, production and trace elements in animal products. Overall, trace element, e.g., Cu, deficiencies were widely prevalent. Environment and certain grazing strategies were intimately related and affected trace element supply whereas cattle type affected trace element status. The effect of trace element status on trace elements in animal products was obvious, whereas the impact on health and production was less clear-cut. Key words: trace elements, minerals, cattle, zebu, Bos indicus, Ethiopia, tropics Introduction and objectivesThroughout the animal kingdom, a certain dietary supply of trace elements (e.g. copper (Cu), zinc (Zn), selenium (Se)) is known to be essential for optimal health (Bender, 2007). In the early days of trace element research in farm animals, numerous studies confirmed their importance for cattle, as supplementation of these elements alleviated elusive symptoms (e.g. claw malformations, muscle skin lesions, diarrhoea) and improved production (McDowell & Arthington, 2005). Following these trials, authors around the globe reported shortages in some trace elements as well as excess in others in natural pastures, indicating an omnipresent risk for trace element imbalance in grazing cattle (Abdelrahman et al., 1998;Mortimer et al., 1999; Govasmark et al., 2005a,b). Indeed, the 1 This is the report of PhD research carried out at Ghent University, under the supervision of prof. dr. ir. Geert Janssens.afrika focus -Volume 27, Nr. 1 [ 88 ] grazing cow is part of the trace element flow from soil to plant and animal and back, and the bovine trace element status is directly influenced by this flow, although many indirect factors are yet to be unravelled (Suttle, 2010). Furthermore, studies investigating the effects of trace element supply on body functions (e.g., immunity: Spears, 2000;Weiss & Spears, 2006;Spears & Weiss, 2008) as well as on production (Ward & Spears, 1997;Engle & Spears, 2000) often produce conflicting results. Additionally, few studies investigated the impact of trace element supply under practical farming conditions (Wichtel, 2003). Finally, the influence of the established trace element status in the animal (e.g deficient, optimal, in excess) on trace element concentrations in edible tissues and milk, is not well understood (Garcia-Vaquero et al., 2011;Rey-Crespo et al., 2013).In tropical areas, poor grasslands remain the primary bottleneck for optimal cattle production (McDowell & Arthington, 2005) and several environmental characteristics (e.g. parent material...

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“…Furthermore, it found that iron is an important component of red blood cells that plays an essential role in haematopoiesis. The use of iron supplementation from wallaby bones may prevent iron deficiency anaemia [24]. …”

Section: Resultsmentioning

confidence: 99%

Characterisation of Bone Beneficial Components from Australian Wallaby Bone

et al. 2016

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Background: Osteoporosis is a condition in which the bones become brittle, increasing the risk of fractures. Complementary medicines have traditionally used animal bones for managing bone disorders, such as osteoporosis. This study aimed to discover new natural products for these types of conditions by determining mineral and protein content of bone extracts derived from the Australian wallaby. Methods: Inductively coupled plasma-mass spectrometry and Fourier transform infrared spectroscopic analysis were used for mineral tests, proteome analysis was using LC/MS/MS and the effects of wallaby bone extracts (WBE)s on calcium deposition and alkaline phosphatase activity were evaluated in osteogenic cells derived from adipose tissue-derived stem cells (ADSCs). Results: Concentrations of calcium and phosphorus were 26.21% and 14.72% in WBE respectively. Additionally, minerals found were wide in variety and high in concentration, while heavy metal concentrations of aluminium, iron, zinc and other elements were at safe levels for human consumption. Proteome analysis showed that extracts contained high amounts of bone remodelling proteins, such as osteomodulin, osteopontin and osteoglycin. Furthermore, in vitro evaluation of WBEs showed increased deposition of calcium in osteoblasts with enhanced alkaline phosphatase activity in differentiated adipose-derived stem cells. Conclusion: Our results demonstrate that wallaby bone extracts possess proteins and minerals beneficial for bone metabolism. WBEs may therefore be used for developing natural products for conditions such as osteoporosis and further investigation to understand biomolecular mechanism by which WBEs prevent osteoporosis is warranted.

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Mineral deficiency status of ranging zebu (Bos indicus) cattle around the Gilgel Gibe catchment, Ethiopia

Cited by 19 publications

References 17 publications

A disparate trace element metabolism in zebu (Bos indicus) and crossbred (Bos indicus × Bos taurus) cattle in response to a copper-deficient diet1

A disparate trace element metabolism in zebu (Bos indicus) and crossbred (Bos indicus × Bos taurus) cattle in response to a copper-deficient diet1

Trace element nutrition in the tropical zebu cattle type. Lessons from the Gilgel Gibe catchment, Ethiopia

Characterisation of Bone Beneficial Components from Australian Wallaby Bone

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