“…In another case, type I hypersensitivity to 2,2′‐methylene‐bis‐(4‐methyl‐6‐ tert ‐butylphenol), an antioxidant used in the manufacture of nitrile, has been confirmed, although this diagnosis relied upon the provision of glove constituent information by the manufacturers 3 . Similar to other reported cases of type I hypersensitivity to synthetic gloves, however, the responsible allergen in our patient was not identifiable using standard clinical investigations 4,5 . This case highlights that although rare, type I hypersensitivity to nitrile glove materials can occur and its diagnosis requires a high index of clinical suspicion.…”