In this paper, a novel liquid refractive index (RI) sensor based on fused tapered photonic crystal fiber (PCF) is proposed. It is fabricated by fusing and tapering a section of PCF which is spliced with two single-mode fibers (SMFs). Due to the fused biconical taper method, the sensor becomes longer and thinner, to make the change of the outside RI has more direct effects on the internal optical field of the PCF, which finally enhances the sensitivity of this sensor. Experimental results show that the transmission spectra of the sensor are red-shifted obviously with the increase of RI. The longer the tapered region of the sensor, the higher the sensitivity is. This sensor has the advantages of simple structure, easy fabrication, high performance and so on, so it has potential applications in RI measurement.Among many refractive index (RI) sensing devices, the fiber-based RI sensors stand out for their small size, high sensitivity, fast response and good stability [1][2][3] . Nowadays, a number of fiber-based RI sensors have been reported, including long period fiber grating (LPFG) [4,5] , fiber Bragg grating (FBG) [6,7] , core offset [8] , imbedded micro air-cavity [9] and many other structures [10,11] . All of them can be applied to the RI sensing field. However, these approaches still have some disadvantages, such as low performance, complicated fabrication and cross sensitivity. Thus, a further research that aims to find a high performance special structure with low complexity is necessary.In this paper, a Mach-Zehnder interference fiber sensor is demonstrated for liquid RI measurement. It is fabricated by just splicing a few-centimeter-long segment of tapered photonic crystal fiber (PCF) between two standard single-mode fibers (SMFs). Utilizing the double beam interference principle, the principle of the sensor is analyzed, and the relationship between the shift of interference spectrum and the change of the liquid RI is obtained. In order to verify the RI sensitivity, five sensors with different tapered lengths were fabricated and applied in a straightforward experiment. The experimental results show that the interference patterns of different sensors have a large red shift as increasing RI. Moreover, the RI sensitivity can be enhanced by increasing the tapered PCF length.As shown in Fig.