Miniaturized surface engineered technologies for multiplex biosensing devices

Srivastava, Vinish Ranjan; Chandra, Pranjal; Kumari, Rohini

doi:10.1002/elan.202200355

Cited by 12 publications

(4 citation statements)

References 173 publications

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“…LFA biosensors are not widely accepted for COVID-19 diagnosis, and the development of innovative nano-bio interfaces is a significant obstacle. 399 Alternative approaches, such as nanomaterial conjugation and colorimetric responses, hold promise for COVID-19 diagnosis. However, widespread implementation in low-resource settings and potential false negative outcomes are significant challenges.…”

Section: Perspectives On Healthcare Management Of Futuristic Infectio...mentioning

confidence: 99%

Engineered two-dimensional nanomaterials based diagnostics integrated with internet of medical things (IoMT) for COVID-19

Sadique,

Yadav,

Khan

et al. 2024

Chem. Soc. Rev.

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Section: Perspectives On Healthcare Management Of Futuristic Infectio...mentioning

confidence: 99%

Engineered two-dimensional nanomaterials based diagnostics integrated with internet of medical things (IoMT) for COVID-19

Sadique,

Yadav,

Khan

et al. 2024

Chem. Soc. Rev.

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“…This creative method keeps pushing analytical chemistry forward, allowing for more thorough and effective molecular analysis. 132…”

Section: Innovations In Biosensing Technologiesmentioning

confidence: 99%

Review—Aptamers and Biomimetic Receptors in Biosensing: Innovations and Applications

Tripathi,

Pandey,

Mishra

et al. 2024

J. Electrochem. Soc.

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The fields of biosensing have been transformed by the discovery of extraordinary molecular recognition components, such as aptamers and biomimetic receptors. Systematic Evolution of Ligands by Exponential Enrichment (SELEX) is a method used to select aptamers, or short sequences of single-stranded DNA (ssDNA) or RNA (ssRNA), based on their unique binding affinity to target molecules. Molecularly imprinted polymers (MIPs) are a type of biomimetic receptor that mimics the selectivity of natural receptors inside a synthetic matrix. They make it possible to identify pathogens, and illness biomarkers with accuracy. Aptamers and biomimetic receptors play crucial roles in various fields including diagnostics, therapeutics, and biosensing. Their high specificity, versatility, and adaptability enable targeted detection, drug delivery, and biomolecule manipulation, thereby contributing to advancements in personalized medicine, biotechnology, and disease diagnosis. Aptamers and biomimetic receptors have been combined with cutting-edge technologies, like nanotechnology and lab-on-a-chip systems, to create biosensors that are quick, portable, and extremely sensitive. These recognition features are anticipated to become more important as technology develops, helping to address global issues, advance biosensing capabilities, and raise people's standard of living everywhere. Recent advancements and innovation on Aptamers and Biomimetic Receptors in Biosensing have been discussed in this review article.

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“…Because of its potential use as a multiplexable POC platform, micro-PADs are able to execute laboratory activities on a micro-scale for the simultaneous detection of several analytes [ 30 ]. When used in fields such as medical, healthcare, and environment, micro-PADs can facilitate the handling and quantitative analysis of fluids [ 31 ].…”

Section: Introductionmentioning

confidence: 99%

Insights into the Fabrication and Electrochemical Aspects of Paper Microfluidics-Based Biosensor Module

Kumari,

Singh,

Azad

et al. 2023

Biosensors

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Over the past ten years, microfluidic paper-based analytical devices (micro-PADs) have attracted a lot of attention as a viable analytical platform. It is expanding as a result of advances in manufacturing processes and device integration. Conventional microfluidics approaches have some drawbacks, including high costs, lengthy evaluation times, complicated fabrication, and the necessity of experienced employees. Hence, it is extremely important to construct a detection system that is quick, affordable, portable, and efficient. Nowadays, micro-PADs are frequently employed, particularly in electrochemical analyses, to replicate the classic standard laboratory experiments on a miniature paper chip. It has benefits like rapid assessment, small sample consumption, quick reaction, accuracy, and multiplex function. The goal of this review is to examine modern paper microfluidics-based electrochemical sensing devices for the detection of macromolecules, small molecules, and cells in a variety of real samples. The design and fabrication of micro-PADs using conventional and the latest techniques have also been discussed in detail. Lastly, the limitations and potential of these analytical platforms are examined in order to shed light on future research.

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Miniaturized surface engineered technologies for multiplex biosensing devices

Cited by 12 publications

References 173 publications

Engineered two-dimensional nanomaterials based diagnostics integrated with internet of medical things (IoMT) for COVID-19

Engineered two-dimensional nanomaterials based diagnostics integrated with internet of medical things (IoMT) for COVID-19

Review—Aptamers and Biomimetic Receptors in Biosensing: Innovations and Applications

Insights into the Fabrication and Electrochemical Aspects of Paper Microfluidics-Based Biosensor Module

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