BackgroundRetroperitoneal partial nephrectomy (RLPN) is the premier treatment for localized renal tumors despite narrow operation space. Many efforts have been taken to facilitate the operation of RLPN, but the optimal resolution remains debatable.ObjectiveTo explore the feasibility of using Mini‐lap to improve workspace and surgical vision in RLPN.Design, Setting, and ParticipantsA multicenter retrospective review of 51 patients who underwent RLPN with Mini‐lap from January 2018 to December 2020 was conducted.Surgical ProcedureStandard RLPN under three poles was performed in all cases. We highlighted the usage of Mini‐lap (Teleflex Minilap percutaneous Surgical System) as a novel retractor in RLPN.Outcome and Measurements and Statical AnalysisDemographics, preoperative, intraoperative, and postoperative outcomes were assessed.Results and LimitationsAll 51 cases completed RLPN with three ports successfully and no conversion to open surgery. The mean diameter of tumors was (3.53 ± 1.05) cm, in which 62.7% (32/51) were located anteriorly. The operation time and warm ischemic time (WIT) were (86.7 ± 15.9) min and (25.6 ± 5) min respectively. Minor complications (Clavien grade 1−2) occurred in 6 cases. The limitations were small sample size, retrospective design, and absence of control.ConclusionsMini‐lap could be used as a mini‐retractor in RLPN, sparing extra assistant ports, expanding workspace, and optimizing vision.Patient SummaryWith highlights of larger workspace and less instrument interference, mini‐lap could be applied in retroperitoneal laparoscopic partial nephrectomy.