Minimal Clinically Important Differences for Measures of Pain, Lung Function, Fatigue, and Functionality in Spinal Cord Injury

Abstract

Objective The objective of this study was to determine the MCIDs for the numerical pain rating scale (NPRS), peak cough flow (PCF), peak expiratory flow (PEF), fatigue severity scale (FSS), and London chest activities of daily living scale (LCADL) in patients with SCI after rehabilitation. Methods Inpatients with SCI from two rehabilitation centres participating in a daily rehabilitation programme were recruited. The NPRS, PCF, PEF, FSS, and LCADL were collected at baseline and discharge. The global rating of change (GRC) scale was performed at discharge. MCIDs were calculated using anchor (linear regression, mean change and receiver operating characteristic curves) and distribution-based methods (0.5 times the baseline standard deviation, standard error of measurement (SEM), 1.96 times SEM, and minimal detectable change) and pooled using arithmetic weighted mean. Results Sixty inpatients with SCI (36 males; 54.5 (15.9) years) participated. On average their rehabilitation programme lasted 7.3 (1.7) weeks. Pooled MCID estimates were − 1.6 points for the NPRS, 69.8 L/min for the PCF, 77.4 L/min for the PEF, 1.1 points for the FSS, and 1.4 points for the LCADL. Conclusion Established MCIDs for NPRS, PCF, PEF, FSS, and LCADL will help health professionals to interpret results and guide rehabilitation interventions in patients with SCI.

A comparison of pain, fatigue, and function between post–COVID-19 condition, fibromyalgia, and chronic fatigue syndrome: a survey study

“…Scores for the FSS range from mild fatigue (≤35), moderate fatigue (36-52), to severe fatigue (≥53). 70,74,111…”

“…Scores for the FSS range from mild fatigue (#35), moderate fatigue (36)(37)(38)(39)(40)(41)(42)(43)(44)(45)(46)(47)(48)(49)(50)(51)(52), to severe fatigue ($53). 70,74,111 2.3.1.6. Patient-Reported Outcomes Information System bank v1.0-fatigue…”

A Case Study of Hypnosis Enhanced Cognitive Therapy for Pain in a Ventilator Dependent Patient during Inpatient Rehabilitation for Spinal Cord Injury

“…For all four sessions, the participant reported stable or reduced pain intensity from before to after hypnosis (see Table 3 ). It is important to highlight that these improvements are considered clinically significant, as they all exceed the suggested 1.6 point clinically significant cut off [ 60 ]. Additionally, the participant consistently reported positive responses to the hypnosis, and experiencing “complete relief” during two of the sessions.…”

The Safety and Feasibility of Transcranial Direct Current Stimulation Combined with Conservative Treatment for Cervicogenic Headaches: A double-blinded randomized control study

“…41 The NPRS has been validated for measuring pain intensity in chronic pain populations with a high test-retest coe cient (r = 0.95) 48 and has a MCID of 1.6 points. 57 The PROMIS pain interference scale has been validated for measuring pain sensitivity in chronic pain populations with a high internal consistency (Cronbach α = 0.94) 49 and an MCID of 9 points. 58 These assessments will be used to evaluate headache frequency and intensity, pain intensity, and pain sensitivity respectively at pre-treatment, post-treatment and at 6-and 12-weeks follow-up.…”