Minimal Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) Determination of Disinfectants in the Pharmaceutical Industry against Pathogens

Farzamfar, Bardia; Norouzi, Siavash; Maleki, Yasamin; Mohammadi, Kosar

doi:10.52547/jhehp.8.4.186

Cited by 1 publication

(2 citation statements)

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“…Bacillus cereus is a Gram-positive, spore-forming rod-shaped bacterium, which is known as a challenge to the food industry due to its ability to sporulate and germinate according to several conditions including temperature, nutrients or pressure (Raso et al, 1998;Wei et al, 2009;van der Voort et al, 2010;Soni et al, 2019a). B. cereus spores can withstand heat treatments (less than 100 °C) (Soni et al, 2019b;Reddy et al, 2021) and are resistant to several food-grade disinfectants (Farzamfar et al, 2022) and desiccation (Ibrahim et al, 2022). The survival strategies of B. cereus spores explain the reason for their prevalence wide range of food products including cooked rice, low-moisture food (such as spices/grains) or dairy-based powders as well as pasteurised and chilled food products (Berthold-Pluta et al, 2019;Liu et al, 2020;Zhang et al, 2020).…”

Section: Introductionmentioning

confidence: 99%

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Hyperspectral imaging and deep learning for detection and quantification of germination in Bacillus cereus spores

Soni,

Dixit,

Brightwell

et al. 2024

Int J of Food Sci Tech

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SummaryGermination of Bacillus cereus spores followed by growth and replication of the vegetative cells in food can result in food poisoning and therefore significant economic and health impacts. This study explores a novel approach to detect and differentiate spores and germinated B. cereus cells using hyperspectral imaging (HSI) in combination with machine learning using three different germination triggers. HSI could successfully differentiate between dormant spores, germinated cells and structural controls (non‐spores). The spectral data in the visible‐near‐infrared range are sensitive to unique structural and chemical characteristics specific to spores, setting them apart from their vegetative counterparts and non‐biological controls. This non‐destructive and robust approach shows significant potential for detection and assessment of the physiological state (dormant or germinated). Therefore, HSI is a potential method for the detection of germination in B. cereus spores and merits further research and validation.

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Section: Introductionmentioning

confidence: 99%

“…B . cereus spores can withstand heat treatments (less than 100 °C) (Soni et al ., 2019b; Reddy et al ., 2021) and are resistant to several food‐grade disinfectants (Farzamfar et al ., 2022) and desiccation (Ibrahim et al ., 2022). The survival strategies of B .…”

Section: Introductionmentioning

confidence: 99%