Minimal suture blepharoplasty: Closure of incisions with autologous fibrin glue

Mandel, Mark A.

doi:10.1007/bf00190076

Cited by 21 publications

(4 citation statements)

References 12 publications

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“…Activated PRP becomes a gel-like material containing fibrin, and fibrin can be used as biologic glue. 21,22 Adding biologic glue to the microablative columns produced using FxCR might assist in the collapse of the columns and enhance the shrinkage of redundant wrinkled skin. Further investigation is needed to elucidate the adjunctive effect of, and the balance between, immediate skin shrinkage and collagen remodelingmediated skin tightening associated with the combination of FxCR and PRP.…”

Section: Discussionmentioning

confidence: 99%

Rapid Healing and Reduced Erythema after Ablative Fractional Carbon Dioxide Laser Resurfacing Combined with the Application of Autologous Platelet-Rich Plasma

Choi

et al. 2011

Dermatologic Surgery

129

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Section: Discussionmentioning

confidence: 99%

Rapid Healing and Reduced Erythema after Ablative Fractional Carbon Dioxide Laser Resurfacing Combined with the Application of Autologous Platelet-Rich Plasma

Choi

et al. 2011

Dermatologic Surgery

129

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“…Additional developments. Several recent reviews have documented a wide variety of additional uses for fibrin sealant (33,34), including its use for achieving hemostasis in patients with coagulation disorders (35); improving results following face lifts (36); repairing dural defects in craniofacial resections (37); assuring hemostasis following tooth extraction in anticoagulated patients (38); closing incisions following blepharoplasty (39); performing safe pancreaticojejunostom y (40); closing rectovaginal and other complex fistulas (41); treating pneumothoraces in premature infants (42); closing multiple ventricular septal defects (43); and re-enforcing choledochotomy closures (44).…”

Section: Discussionmentioning

confidence: 99%

Fibrin Sealant in the United States: Clinical Use at the University of Virginia

Spotnitz

1995

Thromb Haemost

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Surgical hemostasis and tissue adherence would be significantly augmented by an effective adhesive. An ideal tissue adhesive would be widely applicable and have a variety of useful applications. An ultimate agent should have at least the following attributes. The material must be safe so that no significant dangers are associated with its application or the presence of its degradation products. The tissue adhesive must also be effective. The characteristics which are necessary include: Internal bonding strength, surface adherence strength, capacity for enhancing clot formation, and wound healing and tissue regeneration ability. The agent also needs to be readily useable within a period of minutes. The tissue adhesive should be workable so that it is easily shaped and placed in the appropriate location, yet relatively quickly solidifying. The product needs to be reasonably priced so that it is affordable and can be widely used in a cost conscious environment. Most importantly, in the United States today, the adhesive must be approvable by the Food and Drug Administration. This chapter will review the capabilities of fibrin sealant as a surgical tissue adhesive. Experience with it in more than two thousand patients at the University of Virginia Health Sciences Center will be covered in detail. The historical development of fibrin sealant begins with Bergel in 1909 who was the first to use fibrin to establish hemostasis (1). The ability of fibrinogen to function as an adhesive was noted in 1940 by Young and Medawar (2) and the development of fibrin sealant was further advanced by Cronkite, et al. (3) in 1944, when plasma fibrinogen and bovine thrombin were mixed to produce a biologic adhesive. The effectiveness of fibrin sealant was significantly enhanced in 1972 by Matras who developed a more concentrated form of fibrinogen for use in the final adhesive (4). The first commercial forms of fibrin sealant were developed in Europe and a number of different preparations are now being produced for international use. Thus far, however, these forms of fibrin sealant have not been approved for use in the United States. Although, bovine thrombin is commercially available, no source of fibrinogen is presently approved. Thus, individual hospitals have developed methods of producing fibrinogen which can be combined with bovine thrombin, factor XIII, and calcium to produce fibrin sealant. These methods vary from the use of routine American Red Cross cryoprecipitate to M ailing address: Department o f Surgery, B ox 181 University o f V irginia H ealth S cien ces Center

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“…In surgical settings, PRP decreases the frequency of intraoperative and postoperative bleeding at donor and recipient sites, accelerates soft-tissue healing, supports the initial stability of grafted tissue at recipient sites as a result of its cohesive and adhesive nature, promotes rapid vascularization of healing tissue by delivering growth factors and, when used in combination with bone replacement materials it induces regeneration [21]. PRP increases lipocyte survival and improves scar appearance by stimulating mesenchymal stem cells [38][39][40][41][42]57].…”

Section: Use Of Prp In Plastic Surgerymentioning

confidence: 99%

Platlet-Rich Plasma – Review of Literature

Nikolovska

Miladinova²,

Pejkova

et al. 2021

Prilozi

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Wound healing is a dynamic and physiological process for restoring the normal architecture and functionality of damaged tissue. Platelet-rich plasma (PRP) is an autologous whole blood product that contains a large number of platelets in a small volume of plasma with complete set of coagulation factors, which are in physiological concentrations. PRP has haemostatic, adhesive properties and acts supraphysiologically in the process of wound healing and osteogenesis. Platelets play a very important role in the wound healing process by providing growth factors that enhance the rate and quality of wound healing by many different mechanisms. The aim of this review is to describe: the biology of platelets and their role in the wound healing process, the terminology of platelet rich products, PRP preparation, activation and concentration of PRP, as well as the use of PRP in plastic surgery.

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Minimal suture blepharoplasty: Closure of incisions with autologous fibrin glue

Cited by 21 publications

References 12 publications

Rapid Healing and Reduced Erythema after Ablative Fractional Carbon Dioxide Laser Resurfacing Combined with the Application of Autologous Platelet-Rich Plasma

Rapid Healing and Reduced Erythema after Ablative Fractional Carbon Dioxide Laser Resurfacing Combined with the Application of Autologous Platelet-Rich Plasma

Fibrin Sealant in the United States: Clinical Use at the University of Virginia

Platlet-Rich Plasma – Review of Literature

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