“…Furthermore, we have found that MIE after neoadjuvant chemoradiotherapy did not significantly affect the operative time, blood loss, lymph node yield, and length of stay compared with MIE alone [18]. This was similarly reported in a recent retrospective review of 216 consecutive patients who underwent esophagectomy by Yamasaki et al [34]. Despite no statistical difference between physical and tumor status, patients who underwent a minimally invasive esophagectomy had a lower total blood loss, incidence of pulmonary complications, and most importantly, a similar disease-free survival rates at 2 years compared with open esophagectomies [34,35].…”