Minimally Invasive Intact Excision of High-Risk Breast Lesions and Small Breast Cancers: The Intact Percutaneous Excision (IPEX) Registry

Whitworth, Pat W.; Schonholz, S. M.; Phillips, Rogsbert F.; Robertson, Yara; Ruiz, Antonio; Winchester, Susan; Graham, Cathy L.; Simpson, Jean F.; Wernecke, Chloe

doi:10.1245/s10434-019-07212-2

Cited by 5 publications

(2 citation statements)

References 24 publications

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“…25,26 Bleeding during minimally invasive resection affects the quality of the ultrasound image in the surgical field and influences the judgment as to whether the nodule has achieved complete resection. 27 The image quality of ultrasound equipment and the surgeons' level of expertise in ultrasound examinations also impact the quality of nodule resection. 28 The tissue of breast nodule removed by minimally invasive biopsy is fragmented, and this is not conducive to general diagnosis of nodules and may affect the diagnosis of the rapid intraoperative frozen section.…”

Section: Aspects Of Clinical Application Of Ultrasound-guided Minimalmentioning

confidence: 99%

Clinical Value of Ultrasound-Guided Minimally Invasive Biopsy in the Diagnosis or Treatment of Breast Nodules

Gao¹,

Zhu

Xu³

et al. 2020

CMAR

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Purpose To explore the clinical value of ultrasound-guided minimally invasive biopsy of breast nodules for diagnosis and treatment of patients with no positive clinical signs on manual breast examination. Methods We performed a retrospective review of 136 patients with no signs on breast palpation who underwent ultrasound-guided minimally invasive biopsy. A total of 63 patients underwent breast nodule resection from October 2018 to December 2019 at the General Hospital of Central Theater Command of the People’s Liberation Army. Clinical data, including indications for minimally invasive biopsy or resection, pathological and surgical results were retrospectively analyzed. Results A total of 199 patients were studied; 136 underwent minimally invasive biopsy and 63 underwent resection. No severe surgical complications occurred. Minimally invasive biopsy of breast nodules was superior to resection with respect to operation time, incision length, and postoperative complication rate. Conclusion Ultrasound-guided minimally invasive biopsy of breast nodules is feasible for treatment of patients with negative breast nodules and can achieve accurate diagnosis and satisfactory resection.

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Section: Aspects Of Clinical Application Of Ultrasound-guided Minimalmentioning

confidence: 99%

Clinical Value of Ultrasound-Guided Minimally Invasive Biopsy in the Diagnosis or Treatment of Breast Nodules

Gao¹,

Zhu

Xu³

et al. 2020

CMAR

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“…In this issue of Annals of Surgical Oncology, Whitworth et al 1 report their data from their Intact Percutaneous Excision (IPEX) Registry. In a prospective study, 124 cancer patients (both invasive and noninvasive) and 160 patients with high-risk breast lesions (HRLs) underwent a minimally invasive (MI) resection of their lesions using the Intact Breast Lesion Excision System (BLES TM ; Medtronic Inc., Dublin, Ireland).…”

mentioning

confidence: 99%

Intact Excision of Breast Lesions Using BLES™: Is There a Clinical Indication Yet?

Yao

2019

Ann Surg Oncol

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Surgery for Good Prognosis Breast Cancers

McIntosh

2021

Curr Breast Cancer Rep

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Purpose of Review The introduction of mammographic screening programmes has resulted increasing numbers of women with small breast cancers with biologically favourable characteristics. Many of these cancers may represent overdiagnosis, with a resulting treatment burden for women and healthcare costs for providers. Here, current surgical approaches to the treatment of such tumours are reviewed, together with alternative approaches to their management. Recent Findings The surgical treatment of small, screen-detected breast cancers with biologically favourable characteristics has been extrapolated from the management of symptomatic breast cancers. There is no prospective randomised evidence for conventional open surgery compared with other approaches in this setting. A number of minimally invasive techniques, most notable vacuum-assisted excision, have been described for the management of these tumours, but at present, there is a lack of high-quality evidence to support their routine use. There are currently ongoing randomised trials evaluating risk-adapted surgical and minimally invasive approaches to the management of good prognosis disease. Summary It is possible that the surgical treatment of good prognosis screen-detected breast cancers may be de-escalated. However, high-quality evidence from ongoing prospective randomised trials will be required in order to change clinical practice.

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Minimally Invasive Intact Excision of High-Risk Breast Lesions and Small Breast Cancers: The Intact Percutaneous Excision (IPEX) Registry

Cited by 5 publications

References 24 publications

Clinical Value of Ultrasound-Guided Minimally Invasive Biopsy in the Diagnosis or Treatment of Breast Nodules

Clinical Value of Ultrasound-Guided Minimally Invasive Biopsy in the Diagnosis or Treatment of Breast Nodules

Intact Excision of Breast Lesions Using BLES™: Is There a Clinical Indication Yet?

Surgery for Good Prognosis Breast Cancers

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