Minimally invasive nanomedicine: nanotechnology in photo-/ultrasound-/radiation-/magnetism-mediated therapy and imaging

Abstract

This review systematically summarizes the research status, challenges, prospects, and potential bench-to-bedside translation of minimally invasive nanomedicines.

Layered double hydroxide-based nanomaterials for biomedical applications

“…For instance, this can include the structure of organs and blood vessels, physiology of dynamic bioprocess, and bio-distribution of drugs, ranging from the molecular to cellular and/or organ to organism levels. [202][203][204][205] Significant advances have been made over the years in a range of cancer imaging modalities (such as MRI, fluorescence imaging (FLI), computed tomography (CT), ultrasound (US), and photoacoustic imaging (PAI)) which provide structural information. In addition, more modern methods such as positron emission computed tomography (PET) and singlephoton emission computed tomography (SPECT), have been developed, which provide additional information such as physiological characterizations of organs and tissues.…”

“…For instance, this can include the structure of organs and blood vessels, physiology of dynamic bioprocess, and bio-distribution of drugs, ranging from the molecular to cellular and/or organ to organism levels. 202–205…”

Carbon nanomaterials for drug delivery and tissue engineering

“…Cancer is a disease that greatly affects human survival in this century ( Banerjee, 2010 ; Ouyang et al, 2018a ; Ouyang et al, 2018b ). Chemotherapy is, currently, one of the clinical methods for treating cancer, but it has serious side effects and limited and individually differenced therapeutic effects ( Arias, 2011 ; Mohanty et al, 2011 ; Ouyang et al, 2022 ). To overcome the problems (at least some of them) of chemotherapy in cancer therapy strategies, over the past few decades, various drug-delivery systems have been explored with the aim of targeting cancer delivery and controlled release of therapeutic drugs within lesions ( Hubbell and Chilkoti, 2012 ; Lee et al, 2014 ; Chen et al, 2017a ; Ouyang et al, 2021 ).…”

Ultrasound-Induced Drug Release from Stimuli-Responsive Hydrogels

“…A wide variety of polymeric carriers have been developed for ultrasound-responsive drug delivery. The possibilities offered by micelles, nanobubbles, nanodroplets, emulsions, and vesicles have already been thoroughly reviewed [ 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 ]. Consequently, we will only focus on the prospects offered by hydrogels as ultrasound-responsive delivery platforms.…”