2023
DOI: 10.3390/cancers15184585
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Minimally Invasive Radical Nephroureterectomy: 5-Year Update of Techniques and Outcomes

Antonio Franco,
Francesco Ditonno,
Carol Feng
et al.

Abstract: The gold standard treatment for non-metastatic upper tract urothelial cancer (UTUC) is represented by radical nephroureterectomy (RNU). The choice of surgical technique in performing UTUC surgery continues to depend on several factors, including the location and extent of the tumor, the patient’s overall health, and very importantly, the surgeon’s skill, experience, and preference. Although open and laparoscopic approaches are well-established treatments, evidence regarding robot-assisted radical nephrouretere… Show more

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Cited by 8 publications
(3 citation statements)
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“…The differences in OS were in line with prior studies, thus validating the importance in counseling patients of advanced age regarding preoperative optimization and proper patient selection [ 14 ]. Advances in surgical techniques for RARNU, such as complete retroperitoneal access and use of single-port system, as well as the use of NAC, may improve oncologic parameters and decrease perioperative complications in this age group; however, further studies are needed [ 16 ].…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…The differences in OS were in line with prior studies, thus validating the importance in counseling patients of advanced age regarding preoperative optimization and proper patient selection [ 14 ]. Advances in surgical techniques for RARNU, such as complete retroperitoneal access and use of single-port system, as well as the use of NAC, may improve oncologic parameters and decrease perioperative complications in this age group; however, further studies are needed [ 16 ].…”
Section: Discussionmentioning
confidence: 99%
“…A multidimensional geriatric assessment should be considered to determine surgical candidates [14]. RARNU can expand the role of surgical resection for those who may have an increased risk of perioperative complications, such as geriatric patient [15][16][17]. Furthermore, RARNU has demonstrated similar oncological efficacy to open and laparoscopic approaches for UTUC management [15,18,19].…”
Section: Introductionmentioning
confidence: 99%
“…During the recent two decades, there has been a major shift from open RNU towards minimally invasive techniques. Franco et al presented the latest evidence regarding surgical techniques and outcomes of minimally invasive RNU, focusing on robotic RNU [5]. The authors reviewed novel robotic techniques, including single-stage transperitoneal, retroperitoneal, and single-port RNUs.…”
mentioning
confidence: 99%