Minimally Invasive Surgery for Cervical Cancer: Should We Look beyond Squamous Cell Carcinoma?

Giannini, Andrea; D’Oria, Ottavia; Chiàntera, Vito; Margioula‐Siarkou, Chrysoula; Donna, Mariano Catello Di; Terzić, Sanja; Sleiman, Zaki; Laganà, Antonio Simone

doi:10.1080/08941939.2022.2075495

Cited by 28 publications

(19 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In this scenario, the ongoing robot-assisted approach to cervical cancer (RACC) randomized clinical trial is trying to assess the oncologic safety of this technique for the surgical treatment of ECC as compared with standard laparotomy, in terms of recurrence-free survival (RFS), OS and quality of life [ 10 ]. Interestingly, a recent analysis has confirmed that, in women with FIGO stage Ib1-IIa2 cervical adenocarcinoma (CA), there were no significant differences between MIS and open surgery in terms of DFS and OS [ 11 , 12 ]. Nevertheless, further analyses of larger series are needed to better investigate the effect of MIS on the survival rate of ECC patients.…”

Section: Minimally Invasive Surgery: Still a Safe Option?mentioning

confidence: 99%

New Advances in Cervical Cancer: From Bench to Bedside

D’Oria

Corrado

Laganà

et al. 2022

IJERPH

Self Cite

View full text Add to dashboard Cite

Cervical cancer is the most common gynecologic malignancy and the fourth most common cancer in women worldwide. Over the last two decades, minimally invasive surgery (MIS) has emerged as the mainstay in the surgical management of early-stage cervical cancer, bringing advantages such as a lower operative morbidity and shorter hospital stay compared to open surgery, while maintaining comparable oncologic outcomes in numerous retrospective studies. Considering oncological patients, it is mandatory to assess the oncological outcomes and safety of this type of surgery. Moreover, there are different future outlooks on cervical cancer therapy, based on immunotherapy, target therapy, and poly-ADP-ribose polymerases (PARP) inhibitors in combination with each other, and in combination with standard chemotherapy and radiotherapy. The goal is to find an approach that is as personalized as possible.

show abstract

Section: Minimally Invasive Surgery: Still a Safe Option?mentioning

confidence: 99%

New Advances in Cervical Cancer: From Bench to Bedside

D’Oria

Corrado

Laganà

et al. 2022

IJERPH

Self Cite

View full text Add to dashboard Cite

show abstract

“…Transvaginal surgery is a minimally invasive surgery and is currently the preferred treatment for symptomatic ovarian cysts because of its three advantages: less postoperative pain, fewer postoperative complications (i.e., incisional hernia), and improved cosmetic satisfaction. However, despite the popularity of minimally invasive surgery, preoperative evaluation of the ovarian mass is necessary ( 14 ).…”

Section: Discussionmentioning

confidence: 99%

Uterine cervical Müllerian adenosarcoma possibly arising from ovarian cystadenofibroma: A case report and review of the literature

et al. 2023

View full text Add to dashboard Cite

Uterine cervical Müllerian adenosarcoma (MA), a rare malignant tumor of the female reproductive organs, is composed of a benign epithelium and a low-grade malignant stromal component. Because few studies have investigated the clinical management of MA, misdiagnosis often occur. Therefore, we proposed an optimal course of clinical management for patients with MA. MA is possibly a malignant transformation of the cystadenofibroma. In this study, we present a case of a 46-year-old woman who presented with symptoms of MA of the uterine cervix, such as metrorrhagia and a cyst in the cervical canals, after transvaginal excision of the left ovarian mucinous cystadenofibroma.

show abstract

“…ARH therefore has re-emerged as a mainstream treatment for cervical cancer, bringing attention to the effect of abdominal surgeon volume on the complication rates. Despite the finding of poor survival with minimally invasive surgery (MIS) in LACC trail, some studies were still conducted to re-establish the role of MIS and select the appropriate patient for MIS, considering the tumour size and the histological type [32][33][34][35]. Thus, further exploration of the effect of surgeon volume on complications among patients who undergo LRH is also warranted.…”

Section: Discussionmentioning

confidence: 99%

Effect of annualized surgeon volume on major surgical complications for abdominal and laparoscopic radical hysterectomy for cervical cancer in China, 2004–2016: a retrospective cohort study

Liang

Liu

et al. 2023

BMC Women's Health

View full text Add to dashboard Cite

Background Previous studies have suggested that higher surgeon volume leads to improved perioperative outcomes for oncologic surgery; however, the effect of surgeon volumes on surgical outcomes might differ according to the surgical approach used. This paper attempts to evaluate the effect of surgeon volume on complications or cervical cancer in an abdominal radical hysterectomy (ARH) cohort and laparoscopic radical hysterectomy (LRH) cohort. Methods We conducted a population-based retrospective study using the Major Surgical Complications of Cervical Cancer in China (MSCCCC) database to analyse patients who underwent radical hysterectomy (RH) from 2004 to 2016 at 42 hospitals. We estimated the annualized surgeon volumes in the ARH cohort and in the LRH cohort separately. The effect of the surgeon volume of ARH or LRH on surgical complications was examined using multivariable logistic regression models. Results In total, 22,684 patients who underwent RH for cervical cancer were identified. In the abdominal surgery cohort, the mean surgeon case volume increased from 2004 to 2013 (3.5 to 8.7 cases) and then decreased from 2013 to 2016 (8.7 to 4.9 cases). The mean surgeon case volume number of surgeons performing LRH increased from 1 to 12.1 cases between 2004 and 2016 (P < 0.01). In the abdominal surgery cohort, patients treated by intermediate-volume surgeons were more likely to experience postoperative complications (OR = 1.55, 95% CI = 1.11–2.15) than those treated by high-volume surgeons. In the laparoscopic surgery cohort, surgeon volume did not appear to influence the incidence of intraoperative or postoperative complications (P = 0.46; P = 0.13). Conclusions The performance of ARH by intermediate-volume surgeons is associated with an increased risk of postoperative complications. However, surgeon volume may have no effect on intraoperative or postoperative complications after LRH.

show abstract

Minimally Invasive Surgery for Cervical Cancer: Should We Look beyond Squamous Cell Carcinoma?

Cited by 28 publications

References 10 publications

New Advances in Cervical Cancer: From Bench to Bedside

New Advances in Cervical Cancer: From Bench to Bedside

Uterine cervical Müllerian adenosarcoma possibly arising from ovarian cystadenofibroma: A case report and review of the literature

Effect of annualized surgeon volume on major surgical complications for abdominal and laparoscopic radical hysterectomy for cervical cancer in China, 2004–2016: a retrospective cohort study

Contact Info

Product

Resources

About