Minimally invasive surgery for colorectal cancer in advanced age patients

Khalilov, Z. B.; Kalinichenko, A. Yu.; Azimov, R. Kh.; Чиников, М. А.; Panteleeva, I. S.; Kurbanov, Fuat

doi:10.17116/hirurgia2018376-81

Cited by 4 publications

(1 citation statement)

References 13 publications

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“…Laparoscopic radical resection is a common operation for early CRC, which can help complete cancer tissue resection and digestive tract reconstruction by puncture directly to the focus of the cancer with the help of laparoscopic vision. It features with simple operation and advantages in bringing less trauma, less complications, and quick recovery, and its efficacy receives gradual recognition [18][19][20]. However, according to relevant studies in recent years, patients with CRC still suffer recurrence and metastasis after surgery because of the complicated colorectal lymphatic drainage, abundant blood supply, interconnection and densely distribution of CRC cells, difficulty in inhibiting the cells, and their inclination to metastasis.…”

Section: Discussionmentioning

confidence: 99%

Correlation of Presacral Tumour Recurrence with Tumour Metastasis and Long-Term Tumour Recurrence Risk in Patients with Rectal Cancer

Wang¹,

Wu²,

Wang³

et al. 2022

Evidence-Based Complementary and Alternative Medicine

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Objective. To explore the risk factors that affect long-term presacral tumour recurrence in patients with rectal cancer (RC) after radical rectal cancer resection. Methods. In our study, a total of 50 patients with presacral tumour recurrence after radical resection of RC in our hospital between May 2017 and May 2018 were enrolled in the observation group, and the other 50 patients without presacral tumour recurrence after the resection over the same span were enrolled in the control group. The two groups were compared in distant metastatic rate and long-term recurrence, and corresponding K-M curves were drawn. Additionally, the quality of life of the two groups was also compared. Patients in both groups were assigned to a long-term recurrence group or a non-long-term recurrence group based on their long-term recurrence, and a multivariate logistic regression analysis was carried out for analysis of risk factors of long-term recurrence. Results. The two groups were not greatly different in clinical data ( P > 0.05 ). The observation group was higher than the control group in terms of distant metastasis and long-term recurrence ( P < 0.05 ). In addition, the MOS 36-Item Short-Form Health Survey (SF-36) scores of the observation group were all lower than those of the control group in the eight dimensions ( P < 0.05 ). Moreover, tumour diameter (OR: 0.315, 95% CI: 0.118–0.835), differentiation (OR: 2.652, 95% CI: 1.086–6.852), and presacral recurrence (OR: 2.370, 95% CI: 1.263–4.447) were all independent risk factors for long-term recurrence of patients undergoing radical resection of RC. Conclusions. Patients undergoing radical resection of RC face greatly higher risks of presacral tumour distant metastasis and long-term tumour recurrence, and tumour diameter ≥ 5 cm, low-differentiation degree, and presacral recurrence are independent risk factors for long-term recurrence of patients undergoing radical resection of RC. In the future, when performing radical resection of rectal cancer, it is necessary to pay attention to the changes in the above indicators in patients so as to prevent tumour recurrence.

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Section: Discussionmentioning

confidence: 99%