Minimally Invasive Surgery in Pediatric Cancer Patients

Spurbeck, William W.; Davidoff, Andrew M.; Lobe, Thom E.; Rao, Bhaskar N.; Schropp, Kurt P.; Shochat, Stephen J.

doi:10.1245/aso.2004.04.021

Cited by 89 publications

(66 citation statements)

References 8 publications

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“…2,21,22 In recent years, minimally invasive techniques have been widely used to establish a diagnosis, for staging purposes, and for evaluation of recurrent or metastatic disease in children. 3,4,23 The spectrum of malignancies included the whole range of pediatric abdominal, retroperitoneal, and thoracic tumors, such as neuroblastoma, nephroblastoma, hepatoblastoma, rhabdomyosarcoma, teratoma, lymphoma, and numerous others. 3,4,8,13,[23][24][25][26] The conversion rate was less than 5%, the diagnostic accuracy of biopsies was up to 100%, and there were no major intra-or postoperative complications.…”

Section: Discussionmentioning

confidence: 99%

“…The panel considered MIS for biopsy and resection of neuroblastoma as suggested in the literature, [3][4][5]8 except in cases with advanced stage or a need for neurosurgical intervention. Ganglioneuroma was considered suitable for bioptive and ablative MIS.…”

Section: Solid Tumorsmentioning

confidence: 99%

“…Since Holcomb et al 3 reported on a first series of children with cancer undergoing biopsy in 1995, an increasing number of authors confirmed an excellent safety and accuracy of minimally invasive techniques for establishing the diagnosis in children with suspected malignancy. [3][4][5] Minimally invasive techniques have been extensively used for tumor resection in adult cancer patients. 6,7 The feasibility of laparoscopic and thoracoscopic tumor resection has been claimed to be excellent by some authors, who operated on small series of children with neuroblastoma 8,9 and other conditions.…”

mentioning

confidence: 99%

“…6,7 The feasibility of laparoscopic and thoracoscopic tumor resection has been claimed to be excellent by some authors, who operated on small series of children with neuroblastoma 8,9 and other conditions. 4,10,11 However, minimally invasive resection of solid tumors in children is not yet generally accepted, and its feasibility remains to be determined. 4,12,13 The aim of the present study was to evaluate the diagnostic and ablative role of MIS in a consecutive series of children with malignancies.…”

mentioning

confidence: 99%

“…4,10,11 However, minimally invasive resection of solid tumors in children is not yet generally accepted, and its feasibility remains to be determined. 4,12,13 The aim of the present study was to evaluate the diagnostic and ablative role of MIS in a consecutive series of children with malignancies.…”

mentioning

confidence: 99%

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Role of diagnostic and ablative minimally invasive surgery for pediatric malignancies

Metzelder

Kuebler

Shimotakahara

et al. 2007

Cancer

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BACKGROUNDThe use of minimally invasive surgery (MIS) in pediatric cancer is a matter of debate. The diagnostic and ablative roles of MIS were evaluated in a consecutive series of children with malignancies.METHODSA prospective study, including all patients, who underwent abdominal and thoracic surgery for confirmed or highly suspected pediatric cancer was performed from September, 2000, to December, 2005. An interdisciplinary panel approved the indication for minimally invasive or conventional surgery.RESULTSAt a single institution, 301 operations were performed on 276 children with cancer. A minimally invasive approach was attempted in 90 of these patients (30%) and successfully employed in 69 (77%) of the operations. However, 21 operations (23%) were converted to an open approach. Regarding the abdominal operations attempted laparoscopically, 41 abdominal operations for biopsy or staging purposes were attempted laparoscopically (53%), but 6 were converted. In all, 139 abdominal resections were performed and 24 were attempted laparoscopically. Ten of these (42%) were converted. In 34 thoracic operations requiring biopsy, thoracoscopy was attempted in 14 (41%) and was successful in all but 1 (93%). Fifty‐one thoracic tumors were resected and the thoracoscopic approach was attempted in 11 (22%) and successful in 7 (14%). Conversions from a minimally invasive operation to an open procedure occurred mainly due to limited visibility. Three bleeding complications occurred with 1 patient requiring a blood transfusion. In addition, 1 small bowel injury occurred with immediate laparoscopic closure. There were no port site recurrences after a median of 39 months.CONCLUSIONSMIS is a reliable diagnostic tool for pediatric abdominal and thoracic malignancy. The role of ablative MIS in pediatric cancer remains limited. Cancer 2007. © 2007 American Cancer Society.

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