Minimally symptomatic patients with ruptured chordae tendineae due to myxomatous degeneration of the mitral valve

Bergeron, Gary A.

doi:10.1016/0002-9343(86)90273-1

Cited by 5 publications

(2 citation statements)

References 7 publications

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“…MVP has been postulated to have a poor long-term prognosis, especially when complicated with significant mitral regurgitation, atrial or ventricular arrhythmias, congestive heart failure, chordal rupture and infective endocarditis [6, 7, 9, 13, 18, 19, 20, 21, 22, 23, 24, 25, 26], although it rarely results in sudden cardiac death. Among the above-mentioned factors, significant mitral regurgitation is the main factor affecting the outcome of MVP.…”

Section: Discussionmentioning

confidence: 99%

Long-Term Site-Related Differences in the Progression and Regression of the Idiopathic Mitral Valve Prolapse Syndrome

et al. 1999

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The natural history of uncomplicated mitral valve prolapse (MVP) is not clearly understood. To determine the site-related differences in regression and progression of MVP, 112 patients with idiopathic MVP were enrolled in this echocardiographic follow-up study. Cardiovascular complications, including dysarrhythmias (n = 3, 2.7%), overt congestive heart failure (n = 4, 3.6%), progression of mitral regurgitation over one grade (n = 28, 25.0%), newly confirmed chordal rupture (n = 1, 0.9%), and surgical repair (n = 2, 1.8%), were observed in these patients during a follow-up period of 1–13 years (mean, 4.0 ± 2.8 years). Multivariate analysis and Kaplan-Meier analysis revealed that posterior leaflet prolapse and significant mitral regurgitation (grade ≥2) were considerable risks for cardiovascular complications. Regression of MVP was seen in 17 (18.7%) of the anterior prolapse patients; however, new prolapse was observed in 40 (35.7%) patients, mainly in posterior prolapse patients. These results suggest that site-related differences exist in uncomplicated MVP prognosis and that MVP in the posterior leaflet has a poor outcome compared to that in the anterior leaflet.

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Section: Discussionmentioning

confidence: 99%

Long-Term Site-Related Differences in the Progression and Regression of the Idiopathic Mitral Valve Prolapse Syndrome

et al. 1999

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“…This may lead to focal edema in the right upper lobe2. Prior studies have shown that up to 38% of patients with a ruptured chordae tendinae remain asymptomatic in the subacute to chronic setting despite severe mitral insufficiency3,4. In most cases, surgical repair is highly successful5.…”

Section: Report Of Casementioning

confidence: 99%