Minimizing Medical Failure in a Potential Organ Donor Population

Jenkins, Donald H.; Reilly, PM; Anderson, H. Luke; Cs, Deutschman; Aranda, Margaret; Hanson, C. William; Taylor, M; Alavi, A.; Schwab, Christoph

doi:10.1097/00003246-199801001-00435

Cited by 1 publication

(2 citation statements)

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“…Rapid determination of brain death appears to be an important and positive factor in reducing the rate of medical failure for organ donation (Table 4) [57]. By refocusing efforts in the ICU toward aggressive resuscitation, invasive monitoring, and prompt cardiopulmonary resuscitation (CPR) of the potential organ donor, the medical failure rate has dropped to 0% with implementation of this RBD protocol.…”

Section: Medical Failures To Organ Donationmentioning

confidence: 99%

“…By refocusing efforts in the ICU toward aggressive resuscitation, invasive monitoring, and prompt cardiopulmonary resuscitation (CPR) of the potential organ donor, the medical failure rate has dropped to 0% with implementation of this RBD protocol. It has been accompanied by a significant increase in the number of organs donated per potential donor, from 1.5 to 3.3 (p Ͻ 0.05) [57].…”

Section: Medical Failures To Organ Donationmentioning

confidence: 99%

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Improving the Approach to Organ Donation: A Review

1999

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Organ transplantation continues to be hindered by a limited supply of organs. A significant percentage of potential organ donors are lost to either medical failure or inability to obtain consent for donation. In a surgical intensive care unit (ICU) we have refocused our efforts toward aggressive resuscitation, directed by control of coagulopathy, invasive monitoring, and dedicated ICU management while implementing a rapid brain death determination protocol. Over a 6-year period the length of stay until the legal determination of brain death is made has been significantly shortened (12.0 vs. 3.4 hours; p < 0.05), as have associated charges despite this more aggressive approach. As a result, we have eliminated medical failures prior to donation (13% vs. 0%) and increased consent rates (44% vs. 71%; p < 0.05). These efforts have significantly improved the number of organs harvested per eligible donor (1.8 vs. 3.4; p < 0.05). In addition, the number of organs per actual donor has increased and is now markedly greater than the U.S. national average (4.7 vs. 3.7). We believe the approach presented, if widely applied, could potentially improve the current organ supply shortage.

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Section: Medical Failures To Organ Donationmentioning

confidence: 99%

Section: Medical Failures To Organ Donationmentioning

confidence: 99%