Minimum level of jumping exercise required to maintain exercise-induced bone gains in female rats

Ooi, Foong Kiew; Singh, Rabindarjeet; Singh, Harbindar Jeet Singh Gurcharan; Umemura, Yoshihisa

doi:10.1007/s00198-008-0760-6

Cited by 12 publications

(11 citation statements)

References 30 publications

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“…Rats in the jumping group and combined jumping and honey supplementation group were trained to jump using a previously described protocol [21]. Jumping exercises were carried out from 8:30 a.m. to 11:30 a.m. Each rat was subjected to the exercise for 5 minutes duration per day for 5 days per week.…”

Section: Training Programmementioning

confidence: 99%

“…The effects of jumping on bone in these animals depend on forces generated by the hind limbs, thus the hind limb tibias were examined in this study [21]. After removal of the flesh from the tibia bones, they were wrapped in saline-soaked gauze pads to prevent dehydration and put into labeled plastic bags and stored at -80 °C (Heto Ultra Freezer 3410, Denmark) for subsequent measurements at the later date [21].…”

Section: Measurement Of Bone Mineral Density Using Peripheral Quantitmentioning

confidence: 99%

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Changes in Bone Metabolism and Antioxidant Status with Combined Exercise and Honey Supplementation in Young Female Rats

Tavafzadeh¹,

Ooi

Chen³

et al. 2015

JESO

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Open Access Research Articleactivity is through modification in bone turnover which occurs through two fundamentally different processes, i.e. modeling and remodeling with the activities of osteoblast and osteoclast cells in the mechanisms of bone formation and bone resorption [3]. A number of biochemical assays have been described for measuring serum and urinary concentration of markers of bone metabolism [4] that allow a good estimation of bone metabolic processes and have been established as useful parameters in assessing changes in bone turnover. To date, the mechanisms by which combined exercise and dietary intake lead to changes in bone metabolism are not fully understood.Nutritional supplementation is another main factor associated with bone health and development. Aoe et al. [5] reported that as compared to drugs that have a rapid effect, administration of nutrients related to bone metabolism is relatively safe and inexpensive. To date, the effects of different types of supplementation such as calcium, vitamin D, milk, soy and soy protein on bone mass, turnover and mineral density have been reported [6][7][8][9]. One of the nutrients that has long tradition of use within various medical systems and prescribed for variety of uses from ancient time is honey. Ariefdjohan et al. [10] reported that honey has the potential to increase calcium absorption after 2 days of acute feeding in rats. In addition, Hussain et al. [11] reported that honey has similar effects with hormone replacement therapy on bone densitometry in postmenopausal women. Therefore, it was hypothesized that honey may play a role in increasing bone health.Tualang honey is a wild, multi floral honey produced by Apis dorsata bees that form hives on the branches of giant trees named Tualang in the Malaysian rainforest, and it has been reported recently that ovariectomized rats that received Tualang honey showed greater improvements in trabecular bone structure than rats receiving calcium [12], implying the beneficial effects of Tualang honey supplementation on bone. Nevertheless to date, administration of Tualang honey in combination with exercise on bone health and antioxidant status in rats has not been investigated, thus the present study was proposed. AbstractPurpose: To investigate the effects of combined jumping exercise and honey supplementation on bone metabolism and antioxidant status in female rats.

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Section: Training Programmementioning

confidence: 99%

Section: Measurement Of Bone Mineral Density Using Peripheral Quantitmentioning

confidence: 99%

Changes in Bone Metabolism and Antioxidant Status with Combined Exercise and Honey Supplementation in Young Female Rats

Tavafzadeh¹,

Ooi

Chen³

et al. 2015

JESO

View full text Add to dashboard Cite

show abstract

“…) unchanged, is not apparent. It might result from a high impact influencing the bony structure by redistributing the bony materials from the endosteal region toward the periosteal region . This phenomena also triggered a shift in the mass distribution with respect to the bone neutral axis, which significantly increased the polar area moment of inertia (Ip) in the HI cyclic group (Fig.…”

Section: Discussionmentioning

confidence: 96%

Isolated Cyclic Loading During Adolescence Improves Tibial Bone Microstructure and Strength at Adulthood

et al. 2020

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Bone is a unique living tissue, which responds to the mechanical stimuli regularly imposed on it. Adolescence facilitates a favorable condition for the skeleton that enables the exercise to positively influence bone architecture and overall strength. However, it is still dubious for how long the skeletal benefits gained in adolescence is preserved at adulthood. The current study aims to use a rat model to investigate the effects of in vivo low‐ (LI), medium‐ (MI), and high‐ (HI) intensity cyclic loadings applied during puberty on longitudinal bone development, morphometry, and biomechanics during adolescence as well as at adulthood. Forty‐two young (4‐week‐old) male rats were randomized into control, sham, LI, MI, and HI groups. After a 5 day/week for 8 weeks cyclic loading regime applied on the right tibia, loaded rats underwent a subsequent 41‐week, normal cage activity period. Right tibias were removed at 52 weeks of age, and a comprehensive assessment was performed using μCT, mechanical testing, and finite element analysis. HI and MI groups exhibited reduced body weight and food intake at the end of the loading period compared with shams, but these effects disappeared afterward. HI cyclic loading increased BMD, bone volume fraction, trabecular thickness, trabecular number, and decreased trabecular spacing after loading. All loading‐induced benefits, except BMD, persisted until the end of the normal cage activity period. Moreover, HI loading induced enhanced bone area, periosteal perimeter, and moment of inertia, which remained up to the 52nd week. After the normal cage activity at adulthood, the HI group showed increased ultimate force and stress, stiffness, postyield displacement and energy, and toughness compared with the sham group. Overall, our findings suggest that even though both trabecular and cortical bone drifted through age‐related changes during aging, HI cyclic loading performed during adolescence can render lifelong benefits in bone microstructure and biomechanics. © 2020 The Authors. JBMR Plus published by Wiley Periodicals, Inc. on behalf of American Society for Bone and Mineral Research.

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“…11 The present research group has carried out a few previous studies to investigate the effects of exercise alone and also combined effects of exercise with nutritional supplementation on bone health. For instance, Ooi, et al, 12 found that bone mass and strength were significantly higher in jumping rats compared to controls. These findings imply that exercise can enhance bone mass and strength.…”

Section: Introductionmentioning

confidence: 99%

Effects of Chocolate Malt Drink Consumption Combined with Aerobic Dance Exercise on Blood Bone Metabolism Markers, Antioxidant Enzymes and Aerobic Capacity in Young Females

Atiqah¹,

Ooi

Chen³

et al. 2015

Sport Exerc Med Open J

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CitationThe aim of this study was to investigate the effects of combined aerobic dance exercise and chocolate malt drink consumption on bone metabolism markers, antioxidant enzymes and aerobic capacity in young females. Methods: Forty four physically healthy females (19-25 years old) were age and body mass matched and subsequently being assigned into four groups with n=11 per group: Control group (C), Chocolate malt drink group (Cmd), aerobic dance exercise group (Ex) and combined aerobic dance exercise and chocolate malt drink group (CmdEx). Participants' anthropometry and aerobic capacity were measured. Meanwhile, blood samples were taken in order to determine the concentrations of serum total calcium, serum osteocalcin and serum alkaline phosphatase (ALP) (bone formation marker), serum C-terminal telopeptide of type 1 collagen (1CTP) (bone resorption marker) and antioxidant enzyme activities, i.e. Glutathione peroxidase (GPx) and Superoxide dismutase (SOD). Results: At the end of 8 weeks of the intervention period, the percentage of increment in serum osteocalcin was the highest in CmdEx group compared to the other experimental groups. Meanwhile, significant increased in glutathione peroxidase were observed in Ex (p<0.05) and CmdEx (p<0.01) groups after 8 weeks of intervention period. Additionally, the percentage changes in glutathione peroxidase and superoxide dismutase activity were the highest in CmdEx group compared to other groups. There were also significant increases in aerobic capacity in Ex and CmdEx groups. Conclusions: The present study found that generally aerobic dance exercise alone and aerobic dance exercise combined with the consumption of chocolate malt drink elicited more beneficial effects on bone turnover, antioxidant enzyme activities and aerobic capacity compared to chocolate malt drink consumption alone or sedentary without chocolate malt drink consumption in young females.

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Minimum level of jumping exercise required to maintain exercise-induced bone gains in female rats

Abstract: Eight weeks of jumping exercise-induced bone gains could be maintained for a period of 24 weeks with follow-up exercise consisting of 11% to 18% of the initial exercise load.

Cited by 12 publications

References 30 publications

Changes in Bone Metabolism and Antioxidant Status with Combined Exercise and Honey Supplementation in Young Female Rats

Changes in Bone Metabolism and Antioxidant Status with Combined Exercise and Honey Supplementation in Young Female Rats

Isolated Cyclic Loading During Adolescence Improves Tibial Bone Microstructure and Strength at Adulthood

Effects of Chocolate Malt Drink Consumption Combined with Aerobic Dance Exercise on Blood Bone Metabolism Markers, Antioxidant Enzymes and Aerobic Capacity in Young Females

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