1972
DOI: 10.1002/aic.690180403
|View full text |Cite
|
Sign up to set email alerts
|

Minimum realizations and system modeling. I. Fundamental theory and algorithms

Abstract: This review article surveys representative literature on minimum re&-zations and system modeling. This theory makes possible the construction of minimum size state-space models directly from experimental input/output data. Theoretical developments, numerical algorithms, and the connection with other methods of identification of linear systems are covered. Partial minimum realizations which are extensions of the concepts developed are also included. A numerical example illustrates many of the techniques. SCOPE… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1
1

Citation Types

0
14
0

Year Published

1973
1973
1996
1996

Publication Types

Select...
6
2

Relationship

0
8

Authors

Journals

citations
Cited by 21 publications
(14 citation statements)
references
References 14 publications
0
14
0
Order By: Relevance
“…5, 8/26/93, (or other dose surrogate, such as amount metabolized) over a population, rather than to obtain point estimates of dose. One approach to developing population PBPK models is to map a PBPK model * Data onto a compartmental model and thereby establish a relationship between the parameters in the two models (this can be accomplished by adopting system reduction methods (37) and lumping theory (38). The population pharmacokinetic model can then be developed based on the compartmental model using standard population pharmacokinetic software such as the nonlinear mixed effects model (NON-*, MEM) developed at the University of 200 250 300 California at San Francisco (39 Time, population that form heptatoxic benzene metabolite transparameters in a trans-muconaldehyde (40).…”
Section: Results and Discussion Breath Samplesmentioning
confidence: 99%
“…5, 8/26/93, (or other dose surrogate, such as amount metabolized) over a population, rather than to obtain point estimates of dose. One approach to developing population PBPK models is to map a PBPK model * Data onto a compartmental model and thereby establish a relationship between the parameters in the two models (this can be accomplished by adopting system reduction methods (37) and lumping theory (38). The population pharmacokinetic model can then be developed based on the compartmental model using standard population pharmacokinetic software such as the nonlinear mixed effects model (NON-*, MEM) developed at the University of 200 250 300 California at San Francisco (39 Time, population that form heptatoxic benzene metabolite transparameters in a trans-muconaldehyde (40).…”
Section: Results and Discussion Breath Samplesmentioning
confidence: 99%
“…The triple [TAT' 1 , TB, CT' 1 ] will also be a realization. 6 However, the eigenvalues of the matrix A are preserved.…”
Section: Basic Formulationsmentioning
confidence: 99%
“…In view of Eqs. (4) through (6), the measurement function Y(k+\) can be obtained through either of two other algorithms [Eqs. (Al) 2] with realization (Al) will be transformed into the following equation:…”
Section: Appendixmentioning
confidence: 99%
See 1 more Smart Citation
“…5, 8/26/93, (or other dose surrogate, such as amount metabolized) over a population, rather than to obtain point estimates of dose. One approach to developing population PBPK models is to map a PBPK model * Data onto a compartmental model and thereby establish a relationship between the parameters in the two models (this can be accomplished by adopting system reduction methods (37) and lumping theory (38) …”
Section: Results and Discussion Breath Samplesmentioning
confidence: 99%