Minoxidil: Hope for the Bald?

Groot, A. de; Nater, J.P.; Herxheimer, Andrew

doi:10.1016/s0140-6736(87)92281-1

Cited by 34 publications

(3 citation statements)

References 45 publications

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“…Vermutet werden unter anderem eine Verbesserung der Mikrozirkulation im Bereich der dermalen Papille [10] sowie verschiedene andere haarwuchsstimulierende Effekte [13]. Die gute Wirksamkeit topischer 2%iger Minoxidil-Lösung wurde in zahlreichen, gut kontrollierten klinischen Studien belegt [2,5,11,17].…”

Section: Häufigkeit Und Pathogeneseunclassified

Therapie der androgenetischen Alopezie der Frau mit Minoxidil-Lösung

Wolff

2009

Gynäkologische Endokrinologie

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Section: Häufigkeit Und Pathogeneseunclassified

Therapie der androgenetischen Alopezie der Frau mit Minoxidil-Lösung

Wolff

2009

Gynäkologische Endokrinologie

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“…Unter Minoxidillösung ist bei ca. 20-40% der Männer ein Stopp des Haarausfalls zu erwarten,bei 10-20% der Män-ner kommt es auch zum Wiederwachstum kräftiger Terminalhaare [12,54]. Bei Patienten,die wirksam mit Minoxidil behandelt werden, soll ein Stopp des Haarausfalls schon nach ca.8 Wochen erreicht werden können.Zweimal täglich wird 1 ml der Lösung auf die betroffenen Stellen der Kopfhaut aufgetragen.…”

Section: Minoxidilunclassified

Androgenetische Alopezie

et al. 2003

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Androgenetic alopecia is the most common type of hair loss in men and women. The disorder represents a quantitative phenotype with an underlying genetic disposition. So far none of the causative genes have been identified. Under the influence of androgens there is a shortening of the anagen phase as well as a reduction of the cellular hair matrix volume in the involved scalp area. This results in the transformation of thick terminal hair follicles into thin vellus-like hair follicles. Clinically, patients present with an alopecia that follows a defined pattern (pattern baldness) and progresses continuously but in varying degrees. In advanced cases, men may develop baldness with remaining hair exclusively in the temporal and occipital regions. Women are prone to exhibit a more diffuse type of hair loss with pronounced thinning in the parietal region. Whereas the diagnosis of androgenetic alopecia is easy, its treatment is often difficult. The physician is commonly confronted with high patients' expectations regarding hair regrowth. Today, with minoxidil and finasteride, effective therapies are available which can lead to cessation of hair loss. The identification of underlying genes will make a more specific therapy easier to achieve.

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“…If the patient proves to be unacceptable, other treatment options can be discussed. Both Minoxidil 5 or a local solution of Estradiol 6 have been shown to decrease the rate of hair loss in some patients.…”

Section: The Interviewmentioning

confidence: 99%