Miofibroblastoma mamario en paciente posmenopáusica

García-Pineda, Virginia; Cuetos, Ana Esmeralda Cano; Garnica, María Dolores Rodríguez; Corredor, Cristóbal de Valle; Arnanz, F.; Goñí, Álvaro Zapico

doi:10.1016/j.pog.2013.06.001

Cited by 1 publication

(7 citation statements)

References 10 publications

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“…At the ultrasound level, it manifests as a hypoechoic solid mass, well circumscribed, homogeneous and very similar to fibroadenoma 10,13 . On mammography, a single, well-defined, rounded or slightly lobulated lesion can be observed, without calcifications 3,10,11 .…”

Section: Discussionmentioning

confidence: 99%

“…Myofibroblastoma is characterized as a solitary, unilateral, painless and mobile tumor, with a firm consistency and slow growth, where it can take months to years to evolve 3,12,13 . There is no preference for race, and it is not associated with genetic predisposition 13 .…”

Section: Discussionmentioning

confidence: 99%

“…Its size can vary from millimeters to approximately 11 cm or more, with lipomatous or mucoid areas, without cystic degeneration, necrosis or hemorrhage 11,13 . It can be round or oval in shape and have an extramammary location, most commonly along the breast line 9,11,13 .…”

Section: Discussionmentioning

confidence: 99%

“…Microscopically, it appears as a non-encapsulated tumor with lobular growth of spindle cells organized in short intersecting fascicles and interrupted by hyalinized collagen bundles 11 . It usually does not have mitoses or vascular lymphatic invasions 13 . It may have a variable vascular component, formed by small-to medium-sized vessels and numerous mast cells 13 .…”

Section: Discussionmentioning

confidence: 99%

“…It usually does not have mitoses or vascular lymphatic invasions 13 . It may have a variable vascular component, formed by small-to medium-sized vessels and numerous mast cells 13 . There are no breast ducts or lobules within the tumor 11 .…”

Section: Discussionmentioning

confidence: 99%

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Breast myofibroblastoma in a woman: a case report

Reis,

Leitzke,

Ciaccio

et al. 2023

Mastology

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Breast myofibroblastoma is a rare benign neoplasm of mesenchymal origin with fibroblastic and myofibroblastic characterizations. Myofibroblastoma has a higher incidence in men between the ages of 50 and 70 years and is less common in women. It is described as a solitary, unilateral, painless and mobile tumor, with a firm consistency and slow growth. Microscopically, it is a non-encapsulated tumor, with lobular growth, consisting of spindle cells organized in short, intersecting fascicles and interrupted by bundles of hyalinized collagen. On ultrasound, it can manifest as a hypoechoic solid mass, well circumscribed, homogeneous and similar to fibroadenoma; whereas, on mammography, a single, well-defined, rounded or discretely lobulated lesion can be observed, without calcifications. We report here the case of a 58-year-old patient with no previous breast complaints, who presented with changes in ultrasound and mammography examinations performed for breast cancer screening. The examinations revealed a suspicious lump in the left breast, classified as BIRADS 4C. Core biopsy described a low-grade spindle cell neoplasm, showing no signs of invasion, with immunohistochemistry results suggesting myofibroblastoma. As treatment, a sectorectomy was performed, and the reevaluated material confirmed the diagnosis of myofibroblastoma due to the positive expression of the markers calponin, CD34, BCL2 and CD99.

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Section: Discussionmentioning

confidence: 99%