2016
DOI: 10.1016/j.yexcr.2016.09.021
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miR-1207-3p regulates the androgen receptor in prostate cancer via FNDC1/fibronectin

Abstract: Prostate cancer (PCa) is frequently diagnosed in men, and dysregulation of microRNAs is characteristic of many cancers. MicroRNA-1207-3p is encoded at the non-protein coding gene locus PVT1 on the 8q24 human chromosomal region, an established PCa susceptibility locus. However, the role of microRNA-1207-3p in PCa is unclear. We discovered that microRNA-1207-3p is significantly underexpressed in PCa cell lines in comparison to normal prostate epithelial cells. Increased expression of microRNA-1207-3p in PCa cell… Show more

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Cited by 56 publications
(84 citation statements)
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“…Prostate cancer (PCa) is the most commonly diagnosed male cancer in the western world [1,2] . With an estimated 22,800 newly diagnosed men in the US in 2015, PCa is a major cause of cancer morbidity and mortality [3] .…”
mentioning
confidence: 99%
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“…Prostate cancer (PCa) is the most commonly diagnosed male cancer in the western world [1,2] . With an estimated 22,800 newly diagnosed men in the US in 2015, PCa is a major cause of cancer morbidity and mortality [3] .…”
mentioning
confidence: 99%
“…With an estimated 22,800 newly diagnosed men in the US in 2015, PCa is a major cause of cancer morbidity and mortality [3] . Although there has been progress made in the field, several areas of critical unmet needs remain in PCa, such as the molecular mechanisms underlying its development and progression [1,2,[4][5][6] . The complexity of the disease lies in its heterogeneity [1,2,7] .…”
mentioning
confidence: 99%
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