miRNA Target Prediction: Overview and Applications

Rahman, Farjana; Akand, Sajjadul Kadir; Faiza, Muniba; Tabrez, Shams; Rub, Abdur

doi:10.1007/978-981-16-0691-5_14

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Ncrnas and Their Mechanisms Of Action1

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2023

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“…The precursor miRNAs are exported from the nucleus to the cytoplasm and cleaved again by the Dicer enzyme to form miRNA double-stranded bodies containing mature miRNA strands [33]. Mature miRNAs are mainly able to bind to the complementary sites in the 3 -UTR region of the mRNA of target genes, triggering degradation or translational repression of the target mRNAs, and some of the miRNAs can also bind to the 5 -UTR and coding region, thus exerting silencing effects on gene expression [34,35]. Conversely, a few other studies have found that miRNAs can promote gene expression [36,37].…”

Section: Ncrnas and Their Mechanisms Of Actionmentioning

confidence: 99%

The Function and Regulation Mechanism of Non-Coding RNAs in Muscle Development

Yang,

Wu,

Liu

et al. 2023

IJMS

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Animal skeletal muscle growth is regulated by a complex molecular network including some non-coding RNAs (ncRNAs). In this paper, we review the non-coding RNAs related to the growth and development of common animal skeletal muscles, aiming to provide a reference for the in-depth study of the role of ncRNAs in the development of animal skeletal muscles, and to provide new ideas for the improvement of animal production performance.

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