miRNAs and Substances Abuse: Clinical and Forensic Pathological Implications: A Systematic Review
Carla Occhipinti,
Raffaele La Russa,
Naomi Iacoponi
et al.
Abstract:Substance addiction is a chronic and relapsing brain disorder characterized by compulsive seeking and continued substance use, despite adverse consequences. The high prevalence and social burden of addiction are indisputable; however, the available intervention is insufficient. The modulation of gene expression and aberrant adaptation of neural networks are attributed to the changes in brain functions under repeated exposure to addictive substances. Considerable studies have demonstrated that miRNAs are strong… Show more
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