Mirogabalin as a novel calcium channel α2δ ligand for the treatment of neuropathic pain: a review of clinical update
Fei Yang,
Yan Wang,
Mingjie Zhang
et al.
Abstract:Neuropathic pain (NP) is often caused by diabetic neuropathy, chemotherapy, or spinal cord lesions and is associated with significant economic burden and poor quality of life. Sophisticated etiology and pathology recognized different pharmacologic interventions, and hitherto, the reported analgesic efficacy and safety of guideline-recommended drugs are not satisfactory. Overall, this article reviews the mechanism of α2δ ligand, the clinical pharmacokinetics, efficacy, safety and cost-effectiveness of mirogabal… Show more
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