Miscarriage rate comparison of PGS cycles performed with array comparative genome hybridization (aCGH) and next generation sequencing (NGS)

Detailed investigation into the cytogenetic constitution and pregnancy outcome of replacing mosaic blastocysts detected with the use of high-resolution next-generation sequencing

“…Using the same approach, we also found significantly more mosaic embryos in lost pregnancies than in ongoing pregnancies (P¼ .0062) (24). The miscarriage rate after replacing embryos classified as euploid by means of NGS has been determined to be 6%, compared with 13% for aCGH (32) and 20% for qPCR (33).…”