Mise en Evidence De Divers Facteurs De Groupes Sanguins Dans Des Extraits Allergeniques De Poussieres De Maison

Blood Group Activity of Allergenic Preparations

“…Purified active house dust allergen preparations have been confirmed to exhibit A-and B-blood group specificity; the agglutination-inhibition titers of allergen product 72/E were in the same range as recorded by earlier investigators (9,11). Moreover, a number of other allergenic preparations also display A-or B-specificity, though the inhibitory power of most products was quite weak.…”

“…Brocteur & Versie (9) noted that the agglutination-inhibiting potential of the D-fraction of house dust (rich in human serum proteins) was lower than that of the more powerfully skin-active E-fraction. As shown in Table 2, this was con- …”

THE ORIGIN OF SERUM PROTEIN, A, B AND H BLOOD GROUP, AND Gm AND Inv ANTIGENS IN HOUSE DUST

“…Reciprocal of the last positive titre Gm (i) Gm (2) Gm (3) Gm (5) Gm ( less. The low titres of the allotypes in the house dust combined with the fact that positive reactions were found for all the allotypes tested, including Gm (6), suggest that the reactions are artefacts and not indicative of the allotypes. The blood group antigens A, B and H were readily identified in the extract ( Table 3).…”

“…Thus, the serum proteins, albumin, IgG and IgA, and the IgG allotype, Gm(i), have been identified immunologically and are considered to be of human origin (i, 5,9). The red cell antigens A, B, H, Le* and Pi have also been detected (6). Their origin is not certain, since there are several known nonhuman sources of these antigens, and since the Pi antigen has not been identified in saliva or tissues, though it is found on blood cells.…”

A survey of P1‐antibodies in Scottish pigeon fanciers

“…Only those individuals who are Pi(-) may form Ppspecific antibodies and indeed the occurrence of such antibodies in the sera of healthy P i( -) individuals is not an uncommon finding (Issitt & Issitt, 1977). The stimulus for the production of such antibodies is not clear, but P|-like antigens have been identified naturally from various sources; in Ascaris and Lumbricus worms (Prokop & Schlesinger, 1965), in house-dust (Brocteur & Versie, 1967), in gram-negative microorganisms (Roland, 1973) and in pigeon and budgerigar blood . Recently, ovomucoid purified 644 A. C. Munroetal.…”