Misoprostol for Labor Induction in Women With Term Premature Rupture of Membranes

Lin, Monique; Nuthalapaty, Francis S.; Carver, Alissa; Case, Ashley S.; Ramsey, Patrick S.

doi:10.1097/01.aog.0000172425.56840.57

Cited by 103 publications

(37 citation statements)

References 27 publications

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“…31 A recent meta-analysis specifically reviewed the use of misoprostol versus placebo or oxytocin in the patient with term PROM. This analysis determined that labor outcomes using misoprostol were similar to oxytocin infusion for delivery within 24 h of intervention and superior to oxytocin for delivery within 12 h. 34 In addition, misoprostol was not associated with an increase in tachysystole or poor maternal or fetal outcomes.…”

Section: Labor Inductionmentioning

confidence: 99%

Labor induction in the patient with preterm premature rupture of membranes

Packard

Mackeen

2015

Seminars in Perinatology

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Section: Labor Inductionmentioning

confidence: 99%

Labor induction in the patient with preterm premature rupture of membranes

Packard

Mackeen

2015

Seminars in Perinatology

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“…Active management reduces the infectious morbidity associated with a conservative management approach, but it is associated with a high cesarean delivery rate, especially if titrated oxytocin is being used in women with an unfavorable cervix [5]. A meta-analysis [6] shows that misoprostol is both effective and safe for the induction of labor in women with PROM at term. Among the prostaglandins, prostaglandin E2 has been identified as an effective ripening agent [7].…”

Section: Introductionmentioning

confidence: 99%

Misoprostol versus prostaglandin E2 gel for labor induction in premature rupture of membranes after 34 weeks of pregnancy

Zhang¹,

Wang²,

Yu³

et al. 2015

Intl J Gynecology & Obste

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“…Others advocate early intervention with equally good results without increased complications as mentioned above. [4][5][6][7][8] Recently, a great interest has been raised in the use of oral misoprostol for cervical ripening and labor induction and is considered as an alternative agent for induction in cases of PROM. It appears to be an effective method of labour induction with term PROM.…”

Section: Introductionmentioning

confidence: 99%

Induction of Labour Versus Expectant Management for Premature Rupture of Membranes at Term

Bangal

Gulati

Shinde

et al. 2012

Int Jour of Biomed Res

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Background: Premature rupture of the membranes at term is spontaneous rupture of the membranes after 37 wks of the gestations and before the onset of the regular painful uterine contractions .It occurs in ten percent of cases .These cases are either managed conservatively or by immediate induction of labour. Objective: To find out the efficacy and safety of induction of labour versus expectant management in women with premature rupture of membranes beyond 36 weeks gestation, in terms of induction delivery interval, operative interventions, and fetal outcome Material and Methods: A prospective, randomized controlled study was carried out for a period of two years from November 2008 to October 2010 at Rural Medical College, Loni. One hundred pregnant women with term PROM were assigned randomly, each in induction and expectant group. Results: .The mean interval from induction to delivery was significantly shorter in the induction group as compared with expectant group. Incidence of maternal morbidity was comparable in both the groups Neonatal morbidity was higher in expectant group. Incidences of hyper stimulation were more with induction group as compared to expectant group .There was no maternal or perinatal mortality in any group. Intrapartum complications and mode of delivery were similar in both groups. Conclusion: Immediate induction of labour in cases of PROM at term using oral misoprostol resulted in shorter induction delivery interval but increased rate of operative intervention. Maternal morbidity was comparable with induction and expectant line of management. However, neonatal morbidity was higher in expectant group.

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Misoprostol for Labor Induction in Women With Term Premature Rupture of Membranes

Abstract: Misoprostol is an effective and safe agent for induction of labor in women with term premature rupture of membranes. When compared with oxytocin, the risk of contraction abnormalities and the rate of maternal and neonatal complications were similar among the 2 groups.

Cited by 103 publications

References 27 publications

Labor induction in the patient with preterm premature rupture of membranes

Labor induction in the patient with preterm premature rupture of membranes

Misoprostol versus prostaglandin E2 gel for labor induction in premature rupture of membranes after 34 weeks of pregnancy

Induction of Labour Versus Expectant Management for Premature Rupture of Membranes at Term

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