“…16,[18][19][20] Research suggests that its analgesia effect may result from a cascade of physiological interactions between the nervous system and the immune system. 20,21 Gua Sha can attenuate inflammatory cytokines, increase anti-inflammatory factors, elevate NO levels, and inhibit the neuronal response triggered by the activation of microglial cells, leading to antinociception and neuromodulation effects. 17,22 In this context, we proposed the hypothesis that Gua Sha therapy can relieve PD-related pain.…”