Missed Breast Carcinoma: Pitfalls and Pearls

Majid, Aneesa S.; Paredes, Ellen Shaw de; Doherty, Richard D.; Sharma, Neil; Salvador, Xavier

doi:10.1148/rg.234025083

Cited by 211 publications

(121 citation statements)

References 30 publications

Supporting

Mentioning

113

Contrasting

Unclassified

Order By: Relevance

“…Mammography has been established as the primary and standard imaging screening method for breast cancer detection since its superiority was recognised when compared to clinical breast examination (CBE) and breast self-examination (BSE) (Majid et al, 2003). One study reported that the sensitivity and specificity of mammography in detecting invasive breast cancer was 33.3% and 95.0% respectively.…”

Section: Practice and Barriers Of Mammography Among Malaysian Women Imentioning

confidence: 99%

Practice and Barriers of Mammography among Malaysian Women in the General Population

Al-Naggar¹,

Bobryshev²

2012

Asian Pacific Journal of Cancer Prevention

View full text Add to dashboard Cite

Objective: The objective of this study was to determine the practice and barriers of mammography and associated factors among Malaysian women in the general population. Methodology: A cross-sectional study was conducted among 200 women in Shah Alam, Selangor; Malaysia. The questionnaire contained 27 questions and was comprised of two sections; socio-demographic characteristics and practices, knowledge and barriers of mammography. All the data were analyzed using the Statistical Package for the Social Sciences (SPSS) 13.0. Results: Of the 200 Malaysian women who participated in this study, the majority were under the age of 50 years (65.5%), Malay (86%), and married (94.5%). Regarding any family history of cancer in general, the majority of the participants had none (78%). However, some did report a close relative with breast cancer (16.5%). While the majority of them knew about mammography (68%), 15% had had a mammogram once in their life and only 2% had the procedure every two or three years. Univariate analysis showed that age, family history of cancer, family history of breast cancer, regular supplement intake, regular medical check-up and knowledge about mammogram were significantly associated with mammogram practice among the general population (p=0.007, p=0.043, P=0.015, p=0.01, p=0.001, p<0.001; respectively). Multivariate analysis using multiple linear regression test showed that age, regular medical check-up and knowledge about mammography testing were statistically associated with the practice of mammography among the general population in Malaysia (p=0.035, p=0.015 and p<0.001; respectively). Lack of time, lack of knowledge, not knowing where to go for the test and a fear of the test result were the most important barriers (42.5%, 32%, 21%, 20%; respectively). Conclusion: The practice of mammogram screening is low among Malaysian women.

show abstract

Section: Practice and Barriers Of Mammography Among Malaysian Women Imentioning

confidence: 99%

Practice and Barriers of Mammography among Malaysian Women in the General Population

Al-Naggar¹,

Bobryshev²

2012

Asian Pacific Journal of Cancer Prevention

View full text Add to dashboard Cite

show abstract

“…The degree of enhancement is thought to be proportional to the vascularity and hence the suspected grade of the tumor. 2,5 Benign tumors, however, may also enhance. By taking note of the enhancement as a function of time, one can distinguish, in many cases, between benign and malignant lesions.…”

Section: 3mentioning

confidence: 99%

Current Role of Magnetic Resonance Imaging in Breast Imaging: A Primer for the Primary Care Physician

Shah¹,

Shah²,

Greatrex³

2005

The Journal of the American Board of Family Medicine

View full text Add to dashboard Cite

Magnetic resonance imaging (MRI) isMagnetic resonance imaging (MRI) has revolutionized many areas of body imaging. As a noninvasive, nonirradiating imaging tool, interest has steadily been developing as to the specific role of MRI in breast imaging, and whether this modality can assist with early detection and hopefully subsequently decrease the mortality of breast cancer.Mammography has long been used for early detection of and screening for breast cancers. With optimal technique and patient conditions, it has a reported sensitivity between 69% and 90% and a specificity between 10% and 40%. Many factors, including density of breast tissue (ie, younger patients, implants, and post surgical state) can affect these values. Ultrasound has been used as an adjunct to mammography, with particular value in differentiating cystic from solid lesions and in facilitating guided biopsy of suspicious areas. However, ultrasound has limitations, including the possibility of missing microcalcifications [associated with ductal carcinoma in situ (DCIS)] and difficulty in ensuring that the entire breast was imaged with the transducer.

show abstract

“…Breast cancer is the most prevalent cancer in women and is the second leading cause of cancer deaths in women (7). In North America, screening mammography has a false negative rate of 20 to 30% (8,9) and a recall rate of about 10% (10). With a disease prevalence of about 0.3% (11), the vast majority of those recalled will not have cancer.…”

mentioning

confidence: 99%

A half-second glimpse often lets radiologists identify breast cancer cases even when viewing the mammogram of the opposite breast

Evans

Haygood

Cooper

et al. 2016

Proc. Natl. Acad. Sci. U.S.A.

137

View full text Add to dashboard Cite

Humans are very adept at extracting the "gist" of a scene in a fraction of a second. We have found that radiologists can discriminate normal from abnormal mammograms at above-chance levels after a half-second viewing (d′ ∼ 1) but are at chance in localizing the abnormality. This pattern of results suggests that they are detecting a global signal of abnormality. What are the stimulus properties that might support this ability? We investigated the nature of the gist signal in four experiments by asking radiologists to make detection and localization responses about briefly presented mammograms in which the spatial frequency, symmetry, and/or size of the images was manipulated. We show that the signal is stronger in the higher spatial frequencies. Performance does not depend on detection of breaks in the normal symmetry of left and right breasts. Moreover, above-chance classification is possible using images from the normal breast of a patient with overt signs of cancer only in the other breast. Some signal is present in the portions of the parenchyma (breast tissue) that do not contain a lesion or that are in the contralateral breast. This signal does not appear to be a simple assessment of breast density but rather the detection of the abnormal gist may be based on a widely distributed image statistic, learned by experts. The finding that a global signal, related to disease, can be detected in parenchyma that does not contain a lesion has implications for improving breast cancer detection.gist processing | medical image perception | attention | mammography R apid extraction of scene "gist" (1-4) is a very useful aspect of routine visual perception that allows us to allocate our time and attention intelligently when confronted with new visual information (Can I find food here? Is there danger here?). The signals that we extract on our first glimpse of a scene are imperfect but not random. Experts often anecdotally report gistlike experiences with complex images in their domain of expertise. For instance, we have shown that radiologists can distinguish normal from abnormal mammograms at above-chance levels in as little as a quarter of a second, whereas nonexperts cannot (5). The gist of abnormality appears to be a global signal. Radiologists can detect it but cannot even crudely localize the abnormality under these conditions.Detecting the gist of breast cancer might be more than a curiosity, if that signal could be used to improve performance in breast cancer screening. Screening mammography can reduce mortality through early diagnosis of disease (6). Breast cancer is the most prevalent cancer in women and is the second leading cause of cancer deaths in women (7). In North America, screening mammography has a false negative rate of 20 to 30% (8, 9) and a recall rate of about 10% (10). With a disease prevalence of about 0.3% (11), the vast majority of those recalled will not have cancer. Thus, there is significant room for improvement.It has been argued for many years that an initial, global processing step is an i...

show abstract

Missed Breast Carcinoma: Pitfalls and Pearls

Cited by 211 publications

References 30 publications

Practice and Barriers of Mammography among Malaysian Women in the General Population

Practice and Barriers of Mammography among Malaysian Women in the General Population

Current Role of Magnetic Resonance Imaging in Breast Imaging: A Primer for the Primary Care Physician

A half-second glimpse often lets radiologists identify breast cancer cases even when viewing the mammogram of the opposite breast

Contact Info

Product

Resources

About