“…Many authors have reported results of the use of the selfoptimizing control technology that ensure the efficiency of the method applied to a great variety of test-bed examples (e.g., Jensen and Skogestad, 2007a;Jensen and Skogestad, 2007b;Hori and Skogestad, 2007a,b;Lersbamrungsuk et al, 2008;Jagtap et al, 2011;Panahi and Skogestad, 2012;Gera et al, 2013;Jaschke and Skogestad, 2014;Khanam et al, 2014;Graciano et al, 2015). Moreover, application of this technology to different case studies using process simulators has also been reported in the literature (Araujo and Skogestad, 2007a;Araujo and Skogestad, 2007b;Baldea, Araujo, and Skogestad, 2008;Araujo and Skogestad, 2008;Araujo and Shang, 2009a;Araujo and Shang, 2009b;Araujo and Shang, 2009c), and the results showed the feasibility and ease of implementation of the self-optimizing control procedure in such instances. However, much effort and time is usually expended doing many mathematical computations using different pieces of software quite alike from one another.…”