Neglected tropical diseases (NTDs) remain a public health problem among vulnerable, marginalized populations. The crisis in Venezuela has caused poverty, malnutrition, the collapse of the health system and public services that have determined the emergence and re-emergence of infectious diseases that exacerbate the problem of NTDs. Due to its economic impact, the COVID-19 pandemic could lead to greater poverty and aggravate the situation. The WHO aims to eliminate 20 NTDs, including geohelminthiasis, as a public health problem by 2030, which is an ambitious plan for Venezuela. To eliminate NTDs as a public health problem, it is necessary to maximize the efforts of the different health disciplines and the application by governments of environmental sanitation measures and the improvement of the standard of living of the affected populations. However, these measures are complex and take time to implement.