Mitochondria-targeted nanocarriers doubled the toxicity of oxidative phosphorylation and ATP synthesis disruptive insecticides against <i>Spodoptera frugiperda</i>

Hao, Youwu; Liu, Di; Song, Yonghui; Yin, Xinming; Liu, Jia; Na, Risong; Li, Qing X

doi:10.1039/d2en00502f

Environ. Sci.: Nano

2022

DOI: 10.1039/d2en00502f

|View full text |Cite

Mitochondria-targeted nanocarriers doubled the toxicity of oxidative phosphorylation and ATP synthesis disruptive insecticides against Spodoptera frugiperda

Youwu Hao

Di Liu

Yonghui Song

et al.

Abstract: A mitochondria-targeted pesticide delivery system (MSN-CMC-TPP) for the ATP synthesis disruptor chlorfenapyr (Chl) was developed. The MSN-CMC-TPP system enhanced Chl efficacy by inducing mitochondrial damage in Sf9 cells.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2024

Publication Types

Select...

Article2

Relationship

Self Cite0

Independent2

Authors

Journals

Cited by 2 publications

References 48 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Vali@mPEG‐TK‐COS: A Dual‐Function Nano‐Pesticide for Fungicidal Action and Plant Immune Modulation

Li,

Jia,

Xie

et al. 2024

Modern Agriculture

View full text Add to dashboard Cite

Pesticides play a crucial role in safeguarding crops against pathogens and pests, yet the limited bioavailability of conventional formulations leads to excessive usage, causing environmental and health concerns. In this study, we developed a novel intelligent response‐controlled release nano‐pesticide, Vali@mPEG‐TK‐COS, by coupling chitosan oligosaccharide (COS), a plant immunity regulator, and methoxy polyethylene glycols (mPEG) at either end of thioketal (TK), a material responsive to reactive oxygen species (ROS), and incorporating validamycin (Vali) for controlled release. Vali@mPEG‐TK‐COS exhibits ROS‐responsive behaviour, releasing Vali and COS in response to plant ROS bursts, exhibiting dual capabilities in pathogen control and plant immunity induction during pathogenic attacks. Plant disease experiments confirmed the superior efficacy of Vali@mPEG‐TK‐COS against Rhizoctonia solani, surpassing the control effects of Vali or COS alone. This study presents a sophisticated ROS‐responsive controlled‐release nano‐pesticide with dual fungicidal and plant immunomodulatory properties, offering an advanced strategy to enhance the efficiency of existing pesticides and promote sustainable crop production by reducing overall pesticide usage.

show abstract

Vali@mPEG‐TK‐COS: A Dual‐Function Nano‐Pesticide for Fungicidal Action and Plant Immune Modulation

Li,

Jia,

Xie

et al. 2024

Modern Agriculture

View full text Add to dashboard Cite

show abstract

Porous Silica Nanocarriers: Advances in Structural Orientation and Modification to Develop Sustainable Pesticide Delivery Systems

Nasif,

Nuruzzaman,

Naidu

2024

ACS Agric. Sci. Technol.

View full text Add to dashboard Cite

In precision agriculture, nanotechnology has made significant contributions to the development of a smart cropping system through the support of unique properties of nanomaterials. Of the various nanomaterials, porous nanomaterials have an outstanding performance in building a sustainable delivery system for agrochemicals. In pesticide delivery, amorphous porous silica nanomaterials are considered as some of the most suitable options because of their easy synthesis processes, nontoxic nature, structural variation, tunable porous structure, physical and chemical stability, and ease of surface functionality. So far, multiple roles of these materials have been discussed in the literature; however, the influence of porous structure and structural variations toward developing a sustainable delivery system was not clear. A comprehensive review of the compatibility among the porous silica nanocarriers and pesticide molecules is also lacking. Thus, this review discusses the progress of porous amorphous silica nanomaterial synthesis, their structural variation, and surface modification for effective delivery of different pesticides to explore their potential as carriers.

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Mitochondria-targeted nanocarriers doubled the toxicity of oxidative phosphorylation and ATP synthesis disruptive insecticides against Spodoptera frugiperda

Abstract: A mitochondria-targeted pesticide delivery system (MSN-CMC-TPP) for the ATP synthesis disruptor chlorfenapyr (Chl) was developed. The MSN-CMC-TPP system enhanced Chl efficacy by inducing mitochondrial damage in Sf9 cells.

Cited by 2 publications

References 48 publications

Vali@mPEG‐TK‐COS: A Dual‐Function Nano‐Pesticide for Fungicidal Action and Plant Immune Modulation

Vali@mPEG‐TK‐COS: A Dual‐Function Nano‐Pesticide for Fungicidal Action and Plant Immune Modulation

Porous Silica Nanocarriers: Advances in Structural Orientation and Modification to Develop Sustainable Pesticide Delivery Systems

Contact Info

Product

Resources

About