2016
DOI: 10.7287/peerj.preprints.1769v1
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Mitochondrial aerobic respiration is activated during hair follicle stem cells differentiation and its dysfunction retards hair regeneration

Abstract: Background. Emerging researches revealed the essential role of mitochondria in regulating stem/progenitor cell differentiation of neural progenitor cells, mesenchymal stem cells and other stem cells through reactive oxygen species (ROS), Notch or other signaling pathway. And inhibition of mitochondrial synthesis protein resulted in extension of hair loss upon injury. However, alteration of mitochondrial morphology and metabolic function during hair follicle stem cells (HFSCs) differentiation and how it affects… Show more

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